医学理论与实践
醫學理論與實踐
의학이론여실천
The Journal of Medical Theory and Practice
2015年
15期
1975-1976,1982
,共3页
肺炎支原体感染%凝血%免疫功能%临床意义
肺炎支原體感染%凝血%免疫功能%臨床意義
폐염지원체감염%응혈%면역공능%림상의의
Mycoplasma pneumonia infection%Blood coagulation%Immune function%Clinical significance
目的：：探究肺炎支原体感染患儿凝血及免疫功能变化的临床意义。方法：选取2012年1月—2015年2月我院收治的35例肺炎支原体感染患儿为实验组,另选取同期来我院查体的健康体检者35例为对照组,均行凝血及免疫功能检测,分析感染肺炎支原体后凝血与免疫功能改变的临床意义。结果：实验组 FIB 明显较对照组高,PT、APTT 较对照组低,且 CD4/CD8比值、CD3+、CD4+、补体 C4、补体 C3、IgG、IgM、IgA 均较对照组低,CD8+较对照组高,差异有统计学意义(P <0.05)。结论：肺炎支原体感染伴有内源性及激活外源性凝血系统,易抑制患儿凝血及免疫功能,临床上应引起足够重视。
目的：：探究肺炎支原體感染患兒凝血及免疫功能變化的臨床意義。方法：選取2012年1月—2015年2月我院收治的35例肺炎支原體感染患兒為實驗組,另選取同期來我院查體的健康體檢者35例為對照組,均行凝血及免疫功能檢測,分析感染肺炎支原體後凝血與免疫功能改變的臨床意義。結果：實驗組 FIB 明顯較對照組高,PT、APTT 較對照組低,且 CD4/CD8比值、CD3+、CD4+、補體 C4、補體 C3、IgG、IgM、IgA 均較對照組低,CD8+較對照組高,差異有統計學意義(P <0.05)。結論：肺炎支原體感染伴有內源性及激活外源性凝血繫統,易抑製患兒凝血及免疫功能,臨床上應引起足夠重視。
목적：：탐구폐염지원체감염환인응혈급면역공능변화적림상의의。방법：선취2012년1월—2015년2월아원수치적35례폐염지원체감염환인위실험조,령선취동기래아원사체적건강체검자35례위대조조,균행응혈급면역공능검측,분석감염폐염지원체후응혈여면역공능개변적림상의의。결과：실험조 FIB 명현교대조조고,PT、APTT 교대조조저,차 CD4/CD8비치、CD3+、CD4+、보체 C4、보체 C3、IgG、IgM、IgA 균교대조조저,CD8+교대조조고,차이유통계학의의(P <0.05)。결론：폐염지원체감염반유내원성급격활외원성응혈계통,역억제환인응혈급면역공능,림상상응인기족구중시。
Objective:To explore clinical significance of changes of blood coagulation and immune function in children with mycoplasma pneumonia infection.Methods:35 children with mycoplasma pneumoniae infection were chosen on the hospital from January 2012 to February 201 5 as the experimental group.Then another 35 healthy persons who came to the hospital for physical examination at the same time were chosen as control group.All of the people in two groups had taken coagulation and immune function detection for analyzing the clinical significance of changes of blood coagula-tion and immune function in children with mycoplasma pneumonia infection.Results:The FIB of experimental group was significantly higher than the control group.And PT of the group and APTT were lower than that in control group.And the ratio of CD4/CD8,CD3 + ,CD4 + ,complement C4 ,complement C3 ,IgG,IgM,IgA were all lower than those in the control group.CD8 + was relatively higher than the control group.The difference was statistically signifi-cant (P < 0.05).Conclusion:Mycoplasma infection is associated with endogenous and exogenous activation coagulation system which is easy to inhibit the blood coagulation and immune function of children so that enough clinical attention should be paid.
