CAJ | 학술논문

淋巴结转移是影响胰腺癌患者预后的重要因素,然而单纯的淋巴结转移状态(即有或无淋巴结转移)并不能反映胰腺癌的淋巴结转移程度.淋巴结转移率即阳性淋巴结数目除以淋巴结检出数目,既反映了淋巴结转移的程度,又兼顾了淋巴结检出数目的影响,因而在辅助分期、指导治疗和预测预后等各方面都比单纯的淋巴结转移状态更准确.然而由于受淋巴结检出数目和界值不确定性的影响,淋巴结转移率尚无法取代淋巴结转移状态在胰腺癌中的地位,需要进一步的循证医学依据来证实和挖掘其潜在临床应用价值.
림파결전이시영향이선암환자예후적중요인소,연이단순적림파결전이상태(즉유혹무림파결전이)병불능반영이선암적림파결전이정도.림파결전이솔즉양성림파결수목제이림파결검출수목,기반영료림파결전이적정도,우겸고료림파결검출수목적영향,인이재보조분기、지도치료화예측예후등각방면도비단순적림파결전이상태경준학.연이유우수림파결검출수목화계치불학정성적영향,림파결전이솔상무법취대림파결전이상태재이선암중적지위,수요진일보적순증의학의거래증실화알굴기잠재림상응용개치.
Lymphatic metastasis is an important prognostic factor for pancreatic cancer.However,lymphatic metastatic status (N0 or N1) can not reflect the degree of lymphatic metastasis.Lymph node ratio,which is defined as the number of positive lymph nodes divided by total examined lymph nodes,can reflect the degree of lymph metastatic metastasis and give consideration to examined lymph nodes.Lymph node ratio is superior to lymph metastatic status in staging,guiding treatment,and predicting prognosis.However,currently,lymph node ratio cannot replace lymph metastatic status for the undetermined minimum number of examined lymph nodes and cut-off value.Further evidence is needed to prove its clinical value.