中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2015年
22期
8-9
,共2页
心理干预%2型糖尿病%抑郁症%甲状腺激素
心理榦預%2型糖尿病%抑鬱癥%甲狀腺激素
심리간예%2형당뇨병%억욱증%갑상선격소
Psychological intervention%Type 2 diabetes%Depression%Thyroid hormone
目的：探讨心理干预对2型糖尿病(T2DM)伴抑郁症患者血清甲状腺激素水平的影响。方法选取186例T2DM患者为研究对象，采用抑郁评定量表(SDS)得分对患者进行测评诊断，根据诊断结果分为T2DM伴抑郁症患者101例和T2DM不伴抑郁症患者85例。其中将T2DM伴抑郁症患者随机分为心理干预组（常规护理+心理干预）和对照组（常规护理）。结果①T2DM伴抑郁症的患病率为56.99%。②与T2DM不伴抑郁症组比较，T2DM伴抑郁症组患者血清游离三碘甲状腺原氨酸（FT3）水平明显降低（P<0.01），促甲状腺激素（TSH）水平明显升高（P<0.01）。③心理干预后T2DM伴抑郁症患者血清FT3水平较干预前明显升高（t=2.052，P=0.031）；TSH水平、SDS评分较干预前均明显降低（P<0.001）。结论在糖尿病伴抑郁症患者人群中存在甲状腺激素代谢紊乱，心理干预有益于调节甲状腺激素代谢。
目的：探討心理榦預對2型糖尿病(T2DM)伴抑鬱癥患者血清甲狀腺激素水平的影響。方法選取186例T2DM患者為研究對象，採用抑鬱評定量錶(SDS)得分對患者進行測評診斷，根據診斷結果分為T2DM伴抑鬱癥患者101例和T2DM不伴抑鬱癥患者85例。其中將T2DM伴抑鬱癥患者隨機分為心理榦預組（常規護理+心理榦預）和對照組（常規護理）。結果①T2DM伴抑鬱癥的患病率為56.99%。②與T2DM不伴抑鬱癥組比較，T2DM伴抑鬱癥組患者血清遊離三碘甲狀腺原氨痠（FT3）水平明顯降低（P<0.01），促甲狀腺激素（TSH）水平明顯升高（P<0.01）。③心理榦預後T2DM伴抑鬱癥患者血清FT3水平較榦預前明顯升高（t=2.052，P=0.031）；TSH水平、SDS評分較榦預前均明顯降低（P<0.001）。結論在糖尿病伴抑鬱癥患者人群中存在甲狀腺激素代謝紊亂，心理榦預有益于調節甲狀腺激素代謝。
목적：탐토심리간예대2형당뇨병(T2DM)반억욱증환자혈청갑상선격소수평적영향。방법선취186례T2DM환자위연구대상，채용억욱평정량표(SDS)득분대환자진행측평진단，근거진단결과분위T2DM반억욱증환자101례화T2DM불반억욱증환자85례。기중장T2DM반억욱증환자수궤분위심리간예조（상규호리+심리간예）화대조조（상규호리）。결과①T2DM반억욱증적환병솔위56.99%。②여T2DM불반억욱증조비교，T2DM반억욱증조환자혈청유리삼전갑상선원안산（FT3）수평명현강저（P<0.01），촉갑상선격소（TSH）수평명현승고（P<0.01）。③심리간예후T2DM반억욱증환자혈청FT3수평교간예전명현승고（t=2.052，P=0.031）；TSH수평、SDS평분교간예전균명현강저（P<0.001）。결론재당뇨병반억욱증환자인군중존재갑상선격소대사문란，심리간예유익우조절갑상선격소대사。
Objective To investigate the effect of psychological intervention on thyroid hormone levels in type 2 diabetes (T2DM) patients with depression. Methods Self-rating depression scale (SDS) score was used for assessing depression severity among patients. In all, 186 T2DM patients were recruited to the study, which included 101 T2DM patients with depression and 85 T2DM patients without depression. And T2DM patients with depression were randomly divided into psychological intervention group (usual care+psychological intervention) and control group (usual care). Results ①The frequency of T2DM patients with depression in the study participants was 56.99%.②Compared with T2DM patients without depression, subjects with depression had signiifcantly lower serum free thyroid original three iodine glycine (FT3) levels and higher serum thyroid stimulating hormone (TSH) level (all P<0.01).③FT3 level was increased signiifcantly in T2DM patients with depression(t=2.052, P=0.031), while TSH level and SDS scores decreased signiifcantly after the psychological intervention (P<0.001). Conclusion Disorders of thyroid hormone metabolism were observed in T2DM patients with depression. Psychological intervention may play an important role in regulating thyroid hormone metabolism.
