CAJ | 학술논문

干细胞是细胞治疗的潜力平台，在人组织工程和再生医学领域已经得到临床应用。同样，兽医临床也尝试运用干细胞技术治疗马骨关节炎、肌腱炎、蹄叶炎等疾病。目前，在治疗上述疾病时关于使用干细胞种类、数量、次数、运用的治疗方法、治疗时机等问题还需要深入研究。另外，就如何解决免疫安全性、干细胞数量不足等问题也需要技术上的突破。为此，综述干细胞在治疗马软组织疾病时使用干细胞的类型、治疗方法及存在的技术问题。
간세포시세포치료적잠력평태，재인조직공정화재생의학영역이경득도림상응용。동양，수의림상야상시운용간세포기술치료마골관절염、기건염、제협염등질병。목전，재치료상술질병시관우사용간세포충류、수량、차수、운용적치료방법、치료시궤등문제환수요심입연구。령외，취여하해결면역안전성、간세포수량불족등문제야수요기술상적돌파。위차，종술간세포재치료마연조직질병시사용간세포적류형、치료방법급존재적기술문제。
Stem cells (SCs)can represent a promising new platform for cell-based therapies for regenerative medicine.In human medicine,these medical advances about stem cells are already being translated into clinical practice in tissue engineering and regenerative medicine.In parallel,the veterinary profession is loo-king to these technologies to explore novel therapies for chronic diseases,such as,osteoarthritis,tendon-itis and suspensory laminitis in horses.Research efforts must be directed towards determining the optimal type and number of stem cells for each specific clinical application as well as the route of administration,do-sing formulation,dosing and schedule.In addition,insufficient cell numbers of donor and tissue of safety of allogeneic stem cells are also very important and urgent to solve.The purpose of this review was to provide contemporary information as to which type of stem cells should be used,how they should be applied,when they should be applied for the treatment of clinical conditions,and to provide reference for the application of stem cells more widely in the animal clinic.