CAJ | 학술논문

目的：探讨踝肱指数（ABI）对糖尿病足溃疡感染的评价作用，总结抗菌药物效果，以期提高临床治疗水平。方法选取2010年4月至2013年4月85例糖尿病足溃疡感染患者为研究对象，通过多普勒血流探测仪观察患者在足背动脉、胫后动脉和肱动脉的血压值，并结合血压水平计算出ABI值，ABI≤0．9为降低组，ABI 0．9～1．4为正常组，比较两组在血压等方面变化情况，并观察感染程度和预后相关指标情况。结果两组在冠心病、脑血管病和周围血管病变一般合并疾病、BMI、SBP、DBP、HbA1c、TC、TG、HDL‐C、LDL‐C、病程上比较差异有统计学意义（P＜0．05）；且糖尿病足溃疡感染随着病情的加重，在住院天数、治疗费用、愈合时间、愈合情况、截肢和死亡例数上变化也逐渐升高，呈正相关。结论 ABI可作为糖尿病足溃疡感染的前兆，早期抗菌药物治疗预后较为理想。
목적：탐토과굉지수（ABI）대당뇨병족궤양감염적평개작용，총결항균약물효과，이기제고림상치료수평。방법선취2010년4월지2013년4월85례당뇨병족궤양감염환자위연구대상，통과다보륵혈류탐측의관찰환자재족배동맥、경후동맥화굉동맥적혈압치，병결합혈압수평계산출ABI치，ABI≤0．9위강저조，ABI 0．9～1．4위정상조，비교량조재혈압등방면변화정황，병관찰감염정도화예후상관지표정황。결과량조재관심병、뇌혈관병화주위혈관병변일반합병질병、BMI、SBP、DBP、HbA1c、TC、TG、HDL‐C、LDL‐C、병정상비교차이유통계학의의（P＜0．05）；차당뇨병족궤양감염수착병정적가중，재주원천수、치료비용、유합시간、유합정황、절지화사망례수상변화야축점승고，정정상관。결론 ABI가작위당뇨병족궤양감염적전조，조기항균약물치료예후교위이상。
Objective To investigate the ankle‐brachial index (ABI) infected diabetic foot ulcers evaluation role ,summed up the effect of antimicrobial drugs in order to improve the level of clinical treatment .Methods April 2010 April 2013 85 cases of infected diabetic foot ulcers in patients for the study ,observed by Doppler flow detector in patients with dorsal artery ,posterior tibial artery and brachial artery blood pressure values ,combined with ABI blood pressure levels calculated value ,ABIc0 .9 reduce group ,ABI 0 .9 -1 .4 for the control group were compared changes in blood pressure ,etc .,and to observe the extent of infection and prognostic indicators .Results The two groups in coronary heart disease ,cerebrovascular disease and peripheral vascular disease in general comorbidities in BMI ,SBP ,DBP ,HbA1c ,TC ,TG ,HDL‐C ,LDL‐C ,are more significant differences (P<0 .05 ) ;diabetic foot ulcers and infection as the disease worsens ,the number of days of hospitalization ,cost of treatment ,healing ,healing ,ampu‐tation and death on changes in the number of cases has gradually increased ,a positive correlation .Conclusion ABI in‐fected diabetic foot ulcers can be used as a precursor ,early antibiotic treatment and prognosis is better .