CAJ | 학술논문

目的：探讨七氟烷和丙泊酚麻醉对老年肺癌的影响。方法：选取2011年3月－2013年3月106例老年肺癌手术患者为研究对象，分成2组，分别予七氟烷和丙泊酚麻醉，观察治疗后相关指标的变化。结果：治疗后两组睁眼时间、拔管时间、语言答应时间比较差异有统计学意义（P ＜0．05）。MMSE 评分，两组治疗前、治疗8 d 后比较差异无统计学意义（P ＞0．05）。而术后 d1、术后 d3比较两组差异有统计学意义（P ＜0．05）。S100β，两组术前、术后30min 比较差异无统计学意义（P ＞0．05），而术后 d1、术后 d2比较两组差异有统计学意义（P ＜0．05）。结论：七氟烷和丙泊酚麻醉对老年肺癌术后认知功能均有一定影响，但七氟烷影响较小。
목적：탐토칠불완화병박분마취대노년폐암적영향。방법：선취2011년3월－2013년3월106례노년폐암수술환자위연구대상，분성2조，분별여칠불완화병박분마취，관찰치료후상관지표적변화。결과：치료후량조정안시간、발관시간、어언답응시간비교차이유통계학의의（P ＜0．05）。MMSE 평분，량조치료전、치료8 d 후비교차이무통계학의의（P ＞0．05）。이술후 d1、술후 d3비교량조차이유통계학의의（P ＜0．05）。S100β，량조술전、술후30min 비교차이무통계학의의（P ＞0．05），이술후 d1、술후 d2비교량조차이유통계학의의（P ＜0．05）。결론：칠불완화병박분마취대노년폐암술후인지공능균유일정영향，단칠불완영향교소。
Objective:To investigate clinical effects of elderly patients with lung cancer anaesthetized with sevoflu-rane and propofol.Methods:All 106 elderly patients with lung cancer treated with surgery from March 2011 to March 2013 were selected,divided into two groups.One group was given sevoflurane,the other group given propofol.Related indicators were observed.Results:After treatment,the eye -opening time,extrication time,promised spent languages were significantly different between two groups(P <0.05).MMSE score was not significantly different between two groups before and after 8 day treatment,but there were significant differences between two groups after 1 day and 3 day treatment.S100βwere not significantly different between two groups before and after 30min treatment,but there were significant differences between two groups after 1 day and 2 day treatment(P <0.05).Conclusion:Sevoflurane and propofol anesthesia on postoperative cognitive function in elderly lung cancer have some impact,but the impact was lower for sevoflurane.