CAJ | 학술논문

目的：本研究旨在评价南京地区34家医院抗酸药及治疗消化性溃疡药的临床应用情况、特点及发展趋势。方法：采用回顾性分析方法，对南京市34家医院2011~2014年抗酸药及治疗消化性溃疡药的应用品种、销售金额及用药频度进行统计、分析。结果：4年来，南京地区抗酸药及治疗消化性溃疡药的销售金额及用药频度（DDDs）均逐年增加，复合年均增长率（CAGR）分别为14.80%、12.71%；质子泵抑制剂以绝对的优势占据抗酸药及治疗消化性溃疡药市场的主导地位，DDDs占总DDDs的比例达65.60%，CAGR为18.33%。胃黏膜保护剂的销售金额增长幅度最大，CAGR增幅达25.82%。结论：该地区抗酸药及治疗消化性溃疡药应用基本合理，各类药物构成比相对稳定，各种新型胃黏膜保护剂的出现，为临床应用提供较多选择。
목적：본연구지재평개남경지구34가의원항산약급치료소화성궤양약적림상응용정황、특점급발전추세。방법：채용회고성분석방법，대남경시34가의원2011~2014년항산약급치료소화성궤양약적응용품충、소수금액급용약빈도진행통계、분석。결과：4년래，남경지구항산약급치료소화성궤양약적소수금액급용약빈도（DDDs）균축년증가，복합년균증장솔（CAGR）분별위14.80%、12.71%；질자빙억제제이절대적우세점거항산약급치료소화성궤양약시장적주도지위，DDDs점총DDDs적비례체65.60%，CAGR위18.33%。위점막보호제적소수금액증장폭도최대，CAGR증폭체25.82%。결론：해지구항산약급치료소화성궤양약응용기본합리，각류약물구성비상대은정，각충신형위점막보호제적출현，위림상응용제공교다선택。
Objective: To evaluate the situation, characteristics and developing trend of the utilization of antiacids and antiulcer drugs in hospitals of Nanjing area. Methods: The utilization of antiacids and antiulcer drugs in hospitals during the period of 2011-2014 were analyzed statistically in aspects of varieties, consumption sum, DDDs, DDC, etc. Results: In the 4 years, the consumption sum and DDDs of antiacids and antiulcer drugs increased year by year, the annual growth rate were 14.80% and 12.71%, respectively; PPIs always occupied the top position of antiacids and antiulcer drugs market, whose sum of DDDs accounted more than 65.60% for the total DDDs, its CAGR was 18.33%; the consumption sum of gastric mucosal protective drugs increased significantly, its CAGR was 25.82%. Conclusion: The utilization of antiacids and antiulcer drugs in Nanjing area was basically reasonable. The constituent ratios of all kinds of drugs were relatively stable. The emergence of various new protective agents of gastric mucosa provides more choices for clinical application.