CAJ | 학술논문

目的：探讨糖尿病肾病糖化血红蛋白、尿微量蛋白早期诊断价值。方法选择该院2011～2012年收治的120例2型糖尿病肾病患者进行研究，设为观察组，以同期在医院接受体检的健康者120例为健康对照组，对两组受检者进行糖化血红蛋白、尿微量蛋白。结果观察组患者的mALB、HbA1C水平明显高于对照组患者，差异有统计学意义（P＜0．05）；此外，HbA1C水平增高，mALB亦升高，两者具有正相关性。结论糖化血红蛋白水平越高，容易导致糖尿病患者肾脏微血管损伤不断加重，糖化血红蛋白和尿微量蛋白之间呈正相关性。因此糖尿病给患者应及时进行糖化血红蛋白和尿微量蛋白水平，从而有效检测糖尿病的预防和治疗，减轻患者病情，值得在临床上推广应用。
목적：탐토당뇨병신병당화혈홍단백、뇨미량단백조기진단개치。방법선택해원2011～2012년수치적120례2형당뇨병신병환자진행연구，설위관찰조，이동기재의원접수체검적건강자120례위건강대조조，대량조수검자진행당화혈홍단백、뇨미량단백。결과관찰조환자적mALB、HbA1C수평명현고우대조조환자，차이유통계학의의（P＜0．05）；차외，HbA1C수평증고，mALB역승고，량자구유정상관성。결론당화혈홍단백수평월고，용역도치당뇨병환자신장미혈관손상불단가중，당화혈홍단백화뇨미량단백지간정정상관성。인차당뇨병급환자응급시진행당화혈홍단백화뇨미량단백수평，종이유효검측당뇨병적예방화치료，감경환자병정，치득재림상상추엄응용。
Objective To investigate the value of glycated hemoglobin urinary trace protein in early diagnosis of diabetic nephropathyMethods 120 patients with type 2 diabetic nephropathy patients(observation group) and 120 cases of the normal(control group) were studied ,glycated hemoglobin and urine protein of two groups were tested . Results The group of patients mALB ,HbA1C levels were significantly higher than those in control group with a sig‐nificant difference(P<0 .05);addition ,elevated HbA1C levels ,mALB also increased ,there was a positive correlation between the two .Conclusion The higher level in glycated hemoglobin ,easily lead to aggravation of diabetic renal mi‐crovascular injury glycated hemoglobin was positive correlation with urine protein .Therefore ,it is necessary for pa‐tients with diabetes to test glycated hemoglobin and urine protein ,thus effective monitor can do most to prevent and treatment of diabetes ,to improve the patient′s condition ,and to be worthy of applicat by clinical .