检验医学与临床
檢驗醫學與臨床
검험의학여림상
JOURNAL OF LABORATORY MEDICINE AND CLINICAL SCIENCES
2014年
z2期
14-16,17
,共4页
烧伤科%创面培养%金黄色葡萄球菌%耐甲氧西林金黄色葡萄球菌%耐药性
燒傷科%創麵培養%金黃色葡萄毬菌%耐甲氧西林金黃色葡萄毬菌%耐藥性
소상과%창면배양%금황색포도구균%내갑양서림금황색포도구균%내약성
wound culture%staphylococcus aureus%methicillin resistant staphylococcus aureus%drug re-sistance
目的了解2008~2013该院创面培养中金黄色葡萄球菌的耐药性情况,为烧伤科治疗提供依据。方法应用细菌学的方法对2008年1月至2013年12月入住我院烧伤科的患者进行创面培养,VITEK2COMPACT全自动微生物仪进行鉴定,K‐B法进行药敏测试,WHONET5.4软件进行耐药性分析。结果2008年1月至2013年12月从烧伤科送检的创面标本分离出金黄色葡萄球菌212株,其中耐甲氧西林金黄色葡萄球菌(MRSA)193株,MRSA在金黄色葡萄球菌中发生率为91.0%;6年间金黄色葡萄球菌对万古霉素、替考拉宁、利奈唑胺未发现耐药株;对利福平、复方新诺明敏感性尚好,耐药率小于25%;对庆大霉素、左氧氟沙星、克林霉素、红霉素耐药率均达70%以上;对头孢唑啉、苯唑西林、氨苄西林/舒巴坦、青霉素耐药率达到90%以上。结论该院烧伤科创面培养金黄色葡萄球菌耐药率比较严重,MRSA检出率高,应加强金葡菌耐药性监测。
目的瞭解2008~2013該院創麵培養中金黃色葡萄毬菌的耐藥性情況,為燒傷科治療提供依據。方法應用細菌學的方法對2008年1月至2013年12月入住我院燒傷科的患者進行創麵培養,VITEK2COMPACT全自動微生物儀進行鑒定,K‐B法進行藥敏測試,WHONET5.4軟件進行耐藥性分析。結果2008年1月至2013年12月從燒傷科送檢的創麵標本分離齣金黃色葡萄毬菌212株,其中耐甲氧西林金黃色葡萄毬菌(MRSA)193株,MRSA在金黃色葡萄毬菌中髮生率為91.0%;6年間金黃色葡萄毬菌對萬古黴素、替攷拉寧、利奈唑胺未髮現耐藥株;對利福平、複方新諾明敏感性尚好,耐藥率小于25%;對慶大黴素、左氧氟沙星、剋林黴素、紅黴素耐藥率均達70%以上;對頭孢唑啉、苯唑西林、氨芐西林/舒巴坦、青黴素耐藥率達到90%以上。結論該院燒傷科創麵培養金黃色葡萄毬菌耐藥率比較嚴重,MRSA檢齣率高,應加彊金葡菌耐藥性鑑測。
목적료해2008~2013해원창면배양중금황색포도구균적내약성정황,위소상과치료제공의거。방법응용세균학적방법대2008년1월지2013년12월입주아원소상과적환자진행창면배양,VITEK2COMPACT전자동미생물의진행감정,K‐B법진행약민측시,WHONET5.4연건진행내약성분석。결과2008년1월지2013년12월종소상과송검적창면표본분리출금황색포도구균212주,기중내갑양서림금황색포도구균(MRSA)193주,MRSA재금황색포도구균중발생솔위91.0%;6년간금황색포도구균대만고매소、체고랍저、리내서알미발현내약주;대리복평、복방신낙명민감성상호,내약솔소우25%;대경대매소、좌양불사성、극림매소、홍매소내약솔균체70%이상;대두포서람、분서서림、안변서림/서파탄、청매소내약솔체도90%이상。결론해원소상과창면배양금황색포도구균내약솔비교엄중,MRSA검출솔고,응가강금포균내약성감측。
Objective To understand the drug resistance of Staphylococcus aureus in our hospital wound cul‐tures from 2008 to 2013 ,provide the basis for Department of burn treatment .Methods From January 2008 to De‐cember 2013 ,in our hospital wound culture ,Indentification of VITEK2 COMPACT automatic microorganismanalyz‐er ,K‐B method for analysis of drug resistance were tested by WHONET5 .4 software .Results From 2008 January to 2013 December ,212 strains of Staphylococcus aureus were isolated from the Department of burn wound specimens . The methicillin‐resistant Staphylococcus aureus (Methicillin Resistant Staphylococcus Aureus ,MRSA)were 193 stains ,MRSA incidence rate was 91 .0% ,in six years ,Staphylococcus aureus to Vancomycin ,Linezolid ,Teicoplanin found no resistant ;to Rifampin ,Trimethoprim‐sulfamethoxazole showed susceptibility was good ,the resistance rate was lower to 25% ;to Gentamycin ,Levofloxacin ,Clindamycin ,Erytromycin ,the resistance rate was above 70% ;to Ce‐fazolin ,Oxacillin ,Ampicillin‐sulbactam ,Penicillin the resistance rate was more than 90% .Conclusion MRSA resist‐ance rate was very serious in our hospital wound culture ,the detection rate of MRSA was high ,clinical should strengthen the monitoring of drug resistance of Staphylococcus aureus .