中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2015年
15期
113-114,115
,共3页
方巧红%罗敏%龙昌群%史晓丽
方巧紅%囉敏%龍昌群%史曉麗
방교홍%라민%룡창군%사효려
多烯磷脂酰胆碱%外伤性肝破裂%肝损伤%疗效%护理
多烯燐脂酰膽堿%外傷性肝破裂%肝損傷%療效%護理
다희린지선담감%외상성간파렬%간손상%료효%호리
polyene phosphatidyl choline%traumatic rupture of liver%hepatic injury%therapeutic effect%nursing
目的：探讨多烯磷脂酰胆碱对外伤性肝破裂术后肝损伤的修复作用及护理方案。方法将82例患者随机分为对照组和观察组，各41例。对照组给予抗休克、抗感染、止血、补液、改善呼吸、纠正酸碱平衡及电解质紊乱等治疗，观察组加用多烯磷脂酰胆碱注射液治疗。观察两组患者治疗前后丙氨酸氨基转移酶（ALT）、天门冬氨酸氨基转移酶（AST）、总胆红素（TBIL）、血清白蛋白（ALB）及凝血酶原时间（PT）变化情况。结果与对照组相比，观察组患者死亡率显著降低（ P <0.05），总有效率显著升高（ P <0.05）。对照组患者治疗后 ALT和 PT 较治疗前有显著下降（ P <0.05），而 AST，TBIL，ALB 等则未见显著差异。观察组患者治疗后 ALT，AST，TBIL，PT 均较治疗前显著下降（ P <0.05），而 ALB 则未见明显差异。与对照组患者相比，观察组治疗后 ALT，AST，TBIL，PT 均显著下降（ P <0.05）。两组不良反应发生率比较无显著性差异（ P >0.05）。结论多烯磷脂酰胆碱用于外伤性肝破裂术后肝损伤的修复安全、有效。
目的：探討多烯燐脂酰膽堿對外傷性肝破裂術後肝損傷的脩複作用及護理方案。方法將82例患者隨機分為對照組和觀察組，各41例。對照組給予抗休剋、抗感染、止血、補液、改善呼吸、糾正痠堿平衡及電解質紊亂等治療，觀察組加用多烯燐脂酰膽堿註射液治療。觀察兩組患者治療前後丙氨痠氨基轉移酶（ALT）、天門鼕氨痠氨基轉移酶（AST）、總膽紅素（TBIL）、血清白蛋白（ALB）及凝血酶原時間（PT）變化情況。結果與對照組相比，觀察組患者死亡率顯著降低（ P <0.05），總有效率顯著升高（ P <0.05）。對照組患者治療後 ALT和 PT 較治療前有顯著下降（ P <0.05），而 AST，TBIL，ALB 等則未見顯著差異。觀察組患者治療後 ALT，AST，TBIL，PT 均較治療前顯著下降（ P <0.05），而 ALB 則未見明顯差異。與對照組患者相比，觀察組治療後 ALT，AST，TBIL，PT 均顯著下降（ P <0.05）。兩組不良反應髮生率比較無顯著性差異（ P >0.05）。結論多烯燐脂酰膽堿用于外傷性肝破裂術後肝損傷的脩複安全、有效。
목적：탐토다희린지선담감대외상성간파렬술후간손상적수복작용급호리방안。방법장82례환자수궤분위대조조화관찰조，각41례。대조조급여항휴극、항감염、지혈、보액、개선호흡、규정산감평형급전해질문란등치료，관찰조가용다희린지선담감주사액치료。관찰량조환자치료전후병안산안기전이매（ALT）、천문동안산안기전이매（AST）、총담홍소（TBIL）、혈청백단백（ALB）급응혈매원시간（PT）변화정황。결과여대조조상비，관찰조환자사망솔현저강저（ P <0.05），총유효솔현저승고（ P <0.05）。대조조환자치료후 ALT화 PT 교치료전유현저하강（ P <0.05），이 AST，TBIL，ALB 등칙미견현저차이。관찰조환자치료후 ALT，AST，TBIL，PT 균교치료전현저하강（ P <0.05），이 ALB 칙미견명현차이。여대조조환자상비，관찰조치료후 ALT，AST，TBIL，PT 균현저하강（ P <0.05）。량조불량반응발생솔비교무현저성차이（ P >0.05）。결론다희린지선담감용우외상성간파렬술후간손상적수복안전、유효。
Objective Discussion of polyene phosphatidyl choline in traumatic liver rupture repair liver injury after surgery and discuss the nursing plan. Methods 82 cases of traumatic rupture of the liver in postoperative patients with liver injury were randomly divided into control group and observation group, 41 cases in each. The control group was given anti shock, anti infection, hemostasis, infusion, improve breathing, correction of acid - base balance and electrolyte disorders such as treatment. Patients in the observation group based on the use of Polyene Phosphatidyl choline injection treatmentThe two groups before and after treatment in patients with alanine amino-transferase(ALT), and observe the aspartate aminotransferase (AST), total bilirubin (TBIL), serum albumin (ALB) and prothrombin time (PT) changes. In addition, two groups of patients were observed to happen in the process of treatment. Results Compared with the con-trol group, the observation group the mortality of patients decreased significantly, the difference was statistically significant( P < 0. 05) . Compared with the control group, patients in the observation group the total effective rate was significantly increased, the difference was statistically significant( P < 0. 05) . Patients in the control group after treatment, ALT and PT compared with those before treatment was significantly decreased( P < 0. 05 ), while AST, TBIL, ALB were no significant difference. Patients in the observation group after treat-ment, ALT, AST, TBIL, PT significantly lower than before treatment ( P < 0. 05 ) , but ALB has no significant difference compared with before. Compared with patients in the control group, the observation group treatment of ALT, AST, TBIL, PT decreased significantly ( P < 0. 05) . And adverse reactions between the two groups had no significant difference between the rate of occurrence( P > 0. 05) . Conclusion Polyene phosphatidyl choline rupture postoperative repair liver injury is safety, effective for traumatic liver.
