中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2015年
15期
82-83
,共2页
托烷司琼%医护一体式服务%乳腺癌根治术%恶心呕吐%临床疗效
託烷司瓊%醫護一體式服務%乳腺癌根治術%噁心嘔吐%臨床療效
탁완사경%의호일체식복무%유선암근치술%악심구토%림상료효
tropisetron%integrated health care services%radical resection of breast%postoperative nausea and vomiting%clinical curative effect
目的：观察术前给予托烷司琼和医护一体服务预防乳腺癌根治术后恶心呕吐的临床疗效。方法将80例乳腺癌根治术后患者随机分为两组，各40例。对照组于麻醉诱导前静脉缓慢推注平衡液(5 mL)并联合医护一体服务；观察组于麻醉诱导前静脉缓慢推注托烷司琼（0.1 mg / kg）并联合医护一体服务，观察并记录患者行乳腺癌根治术后48 h 内恶心、呕吐发生率、程度及不良反应。结果治疗后48 h，对照组、观察组恶心、呕吐发生率为82.50%和45.00%( P <0.05)，观察组呕吐频次显著下降，呕吐停止时间显著缩短（ P <0.05）；两组患者治疗后均出现镇静等轻微不良反应，但未见明显差异。结论术前给予托烷司琼和医护一体服务对预防乳腺癌根治术后恶心、呕吐有显著作用，且未增加不良反应，适合临床推广。
目的：觀察術前給予託烷司瓊和醫護一體服務預防乳腺癌根治術後噁心嘔吐的臨床療效。方法將80例乳腺癌根治術後患者隨機分為兩組，各40例。對照組于痳醉誘導前靜脈緩慢推註平衡液(5 mL)併聯閤醫護一體服務；觀察組于痳醉誘導前靜脈緩慢推註託烷司瓊（0.1 mg / kg）併聯閤醫護一體服務，觀察併記錄患者行乳腺癌根治術後48 h 內噁心、嘔吐髮生率、程度及不良反應。結果治療後48 h，對照組、觀察組噁心、嘔吐髮生率為82.50%和45.00%( P <0.05)，觀察組嘔吐頻次顯著下降，嘔吐停止時間顯著縮短（ P <0.05）；兩組患者治療後均齣現鎮靜等輕微不良反應，但未見明顯差異。結論術前給予託烷司瓊和醫護一體服務對預防乳腺癌根治術後噁心、嘔吐有顯著作用，且未增加不良反應，適閤臨床推廣。
목적：관찰술전급여탁완사경화의호일체복무예방유선암근치술후악심구토적림상료효。방법장80례유선암근치술후환자수궤분위량조，각40례。대조조우마취유도전정맥완만추주평형액(5 mL)병연합의호일체복무；관찰조우마취유도전정맥완만추주탁완사경（0.1 mg / kg）병연합의호일체복무，관찰병기록환자행유선암근치술후48 h 내악심、구토발생솔、정도급불량반응。결과치료후48 h，대조조、관찰조악심、구토발생솔위82.50%화45.00%( P <0.05)，관찰조구토빈차현저하강，구토정지시간현저축단（ P <0.05）；량조환자치료후균출현진정등경미불량반응，단미견명현차이。결론술전급여탁완사경화의호일체복무대예방유선암근치술후악심、구토유현저작용，차미증가불량반응，괄합림상추엄。
Objective To observe the effect of tropisetron before radical mas - tectomy and integrated health care services to prevent breast cancer radical postoperative nausea and vomiting. Methods 80 radical mas - tectomy patients randomly divided into 2 groups, two groups separately 40 patients, patients in control group: received intravenous inject buffer slowly (5 mL) and special management of in-tegrated health care services after operation; and patient in tropisetron group: received intravenous inject tropisetron slowly (0. 1 mg / kg) and special management of integrated health care services after operation, Observe and record the occurrence of PONV and other ad-verse reactions in three groups of patients in 48 h. Results After treatment 48 h, the occurrence rate of PONV in control group and tropisetron group were 82. 50% and 45. 00% ( P < 0. 05 ), the frequency of vomiting is decreased in tropisetron group and the vomiting is shorter than control group( P < 0. 05). Patients in both groups after the treatment of mild sedation and other side effects, no signifi-cant difference was not statistically significant. Conclusion The effect of tropisetron before radical mas - tectomy and integrated health care services to prevent breast cancer radical postoperative nausea and vomiting had a significant effects. it is suitable for promotion.
