CAJ | 학술논문

辛香料成分具有多种药理活性，但溶解度差，生物利用度低的特点限制了其制剂的发展。缓控释制剂能够在提高药物溶解度的基础上，延缓药物的释放行为，从而提高药物的生物利用度。本文综合国内外辛香料成分缓控释制剂的研究概况，为进一步地开发和利用辛香料活性成分提供参考依据。
신향료성분구유다충약리활성，단용해도차，생물이용도저적특점한제료기제제적발전。완공석제제능구재제고약물용해도적기출상，연완약물적석방행위，종이제고약물적생물이용도。본문종합국내외신향료성분완공석제제적연구개황，위진일보지개발화이용신향료활성성분제공삼고의거。
The spices, with a wide range of remarkable pharmacological effects, were limited in developing clinical drugs because of their poor solubility, high irritation and low bioavailability. Controlled release preparations can delay the release of drugs on the basis of solubility enhancement to improve bioavailability. The research on spice ingredient-loaded controlled release preparations was sum-marized in the paper for the further development of spice active ingredients.