中国药师
中國藥師
중국약사
CHINA PHARMACIST
2015年
8期
1357-1359
,共3页
肾上腺素%布地奈德%地塞米松%雾化吸入%儿童急性喉炎
腎上腺素%佈地奈德%地塞米鬆%霧化吸入%兒童急性喉炎
신상선소%포지내덕%지새미송%무화흡입%인동급성후염
Epinephrine%Budesonide%Dexamethasone%Atomization inhalation%Children with acute laryngitis
目的：：对比肾上腺素联合布地奈德雾化吸入与地塞米松雾化吸入治疗儿童急性喉炎的临床疗效及安全性。方法：68例急性喉炎患儿随机分成两组,均给予常规综合治疗,在此基础上,对照组30例予地塞米松雾化吸入；观察组38例予肾上腺素联合布地奈德雾化吸入。观察两组患儿治疗12,24,72 h临床效果、临床症状体征消失时间及药品不良反应。结果：观察组患儿治疗12,24,72 h后临床效果均显著优于对照组(P<0.05)；治疗72 h,观察组治愈率为71.05%,明显高于对照组的56.67%(P<0.05)。观察组临床症状体征消失时间均显著早于对照组(P<0.05)；两组患儿均未见明显药品不良反应。结论：肾上腺素联合布地奈德雾化吸入治疗儿童急性喉炎临床效果优于地塞米松雾化吸入,能迅速改善患儿临床症状体征,且安全性好,值得临床推广应用。
目的：：對比腎上腺素聯閤佈地奈德霧化吸入與地塞米鬆霧化吸入治療兒童急性喉炎的臨床療效及安全性。方法：68例急性喉炎患兒隨機分成兩組,均給予常規綜閤治療,在此基礎上,對照組30例予地塞米鬆霧化吸入；觀察組38例予腎上腺素聯閤佈地奈德霧化吸入。觀察兩組患兒治療12,24,72 h臨床效果、臨床癥狀體徵消失時間及藥品不良反應。結果：觀察組患兒治療12,24,72 h後臨床效果均顯著優于對照組(P<0.05)；治療72 h,觀察組治愈率為71.05%,明顯高于對照組的56.67%(P<0.05)。觀察組臨床癥狀體徵消失時間均顯著早于對照組(P<0.05)；兩組患兒均未見明顯藥品不良反應。結論：腎上腺素聯閤佈地奈德霧化吸入治療兒童急性喉炎臨床效果優于地塞米鬆霧化吸入,能迅速改善患兒臨床癥狀體徵,且安全性好,值得臨床推廣應用。
목적：：대비신상선소연합포지내덕무화흡입여지새미송무화흡입치료인동급성후염적림상료효급안전성。방법：68례급성후염환인수궤분성량조,균급여상규종합치료,재차기출상,대조조30례여지새미송무화흡입；관찰조38례여신상선소연합포지내덕무화흡입。관찰량조환인치료12,24,72 h림상효과、림상증상체정소실시간급약품불량반응。결과：관찰조환인치료12,24,72 h후림상효과균현저우우대조조(P<0.05)；치료72 h,관찰조치유솔위71.05%,명현고우대조조적56.67%(P<0.05)。관찰조림상증상체정소실시간균현저조우대조조(P<0.05)；량조환인균미견명현약품불량반응。결론：신상선소연합포지내덕무화흡입치료인동급성후염림상효과우우지새미송무화흡입,능신속개선환인림상증상체정,차안전성호,치득림상추엄응용。
To compare the clinical efficacy and safety of atomization inhalation of epinephrine combined with budes-onide and dexamethasone in the treatment of children with acute laryngitis. Methods:Totally 68 cases of children with acute laryngitis were randomly divided into two groups. The two groups were given the conventional therapy, and 30 cases in the control group were giv-en dexamethasone inhalation additionally, and the treatment group was given epinephrine combined with budesonide inhalation addition-ally. The clinical effect in 12, 24 and 72h, clinical symptom disappearance time and adverse reactions in the two groups were ob-served. Results:The clinical effect of the treatment group in 12, 24 and 72h was better than that in the control group. 72h after the treatment, 17 cases in the control group were cured, and the curative rate was 56. 67%, while 27 cases in the treatment group were cured with the curative rate of 71. 05%. The disappearance time of dyspnea and stridor, barking cough, hoarseness and the other clini-cal symptoms in the treatment group was significantly shorter than that in the control group, and the difference was statistically signifi-cant (P<0. 05). The two groups had no obvious adverse reaction. Conclusion:The clinical effect of the combination of epinephrine and budesonide inhalation in the treatment of children with acute laryngitis is better than that of dexamethasone inhalation, and the combination is safe and effective, which is worthy of clinical application.
