CAJ | 학술논문

目的：：观察阿仑磷酸钠联合金天格胶囊治疗绝经后骨质疏松( PMOP)的临床疗效。方法：98例PMOP患者随机分为阿仑磷酸钠片组(阿仑磷酸钠片70 mg,po,每周1次)32例、金天格胶囊组(1.2 g,po,tid)32例和联用组(阿仑磷酸钠片70 mg,po,每周1次+金天格胶囊1.2 g,po,tid)34例,连续治疗6个月,比较3组患者治疗前后的临床症状评分、骨密度( BMD)、血钙、血磷、碱性磷酸酶( AKP)及肝肾功能等各项指标的变化数据。结果：治疗6个月后,联用组症状评分下降幅度明显优于阿仑磷酸钠片组和金天格胶囊组(P<0.05)；3组的BMD均较治疗前明显上升,且联用组改善更明显(P<0.05)。结论：阿仑磷酸钠联合金天格治疗PMOP的效果显著,能够有效改善临床症状,明显增加骨密度,值得推广应用。
목적：：관찰아륜린산납연합금천격효낭치료절경후골질소송( PMOP)적림상료효。방법：98례PMOP환자수궤분위아륜린산납편조(아륜린산납편70 mg,po,매주1차)32례、금천격효낭조(1.2 g,po,tid)32례화련용조(아륜린산납편70 mg,po,매주1차+금천격효낭1.2 g,po,tid)34례,련속치료6개월,비교3조환자치료전후적림상증상평분、골밀도( BMD)、혈개、혈린、감성린산매( AKP)급간신공능등각항지표적변화수거。결과：치료6개월후,련용조증상평분하강폭도명현우우아륜린산납편조화금천격효낭조(P<0.05)；3조적BMD균교치료전명현상승,차련용조개선경명현(P<0.05)。결론：아륜린산납연합금천격치료PMOP적효과현저,능구유효개선림상증상,명현증가골밀도,치득추엄응용。
To explore the clinical effect of alendronate combined with Jintiange capsules in the treatment of postmeno-pausal osteoporosis ( PMOP) . Methods:Ninety-eight cases of PMOP patients were randomly divided into three groups. The combina-tion treatment group (34 cases) was treated with alendronate tablets combined with Jintiange capsules, while the control group A (32 cases) and the control group B (32 cases) was respectively treated with alendronate tablets and Jintiange capsules, and the treatment course was six months. The changes of the clinical symptom score, bone mineral density ( BMD) , serum calcium, serum phosphorus, AKP, hepatorenal function and so on before and after the treatment were recorded. Results:After the six-month treatment, the clinical symptom score of the treatment group was much better than that in the two control groups(P<0. 05). BMD in the three groups was in-creased after the treatment(P<0. 05), and the increase in the treatment group was more notable than that in the two control groups(P<0. 05). Conclusion:Alendronate combined with Jintiange capsules can effectively improve BMD and relieve clinical symptoms in the patients with PMOP, which is worthy of promoted application.