中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2015年
20期
147-148
,共2页
随机对照试验%类风湿关节炎%中西医结合%疗效%荟萃分析
隨機對照試驗%類風濕關節炎%中西醫結閤%療效%薈萃分析
수궤대조시험%류풍습관절염%중서의결합%료효%회췌분석
Randomized controlled trials%Rheumatoid arthritis%The integrative medicine%Efficacy%Meta-analysis
目的：对中西医结合治疗类风湿关节炎的文献进行荟萃分析，为临床治疗类风湿关节炎提供依据。方法：对2008年1月-2014年1月维普、万方等数据库收录的有关“中西医结合治疗类风湿关节炎”的随机对照试验进行检索，应用Jadad量表对纳入的文献报道进行评价、分析，并通过统计学软件Review Manager 5.0对纳入文献实施荟萃分析。结果：共纳入文献12篇，病例总数为960例，采用中西医结合治疗的500例类风湿关节炎患者为研究组，采用西医治疗的460例类风湿关节炎患者为对照组，荟萃分析显示OR＝0.32，95% CI＝2.35～4.70，Z＝6.49，P<0.00001。结论：对类风湿关节炎患者实施中西医结合疗法，显著减少了单用西药治疗所引起的副反应情况，使用药的耐受性明显增强，且治疗总有效率显著高于单用西药治疗，值得推广应用。
目的：對中西醫結閤治療類風濕關節炎的文獻進行薈萃分析，為臨床治療類風濕關節炎提供依據。方法：對2008年1月-2014年1月維普、萬方等數據庫收錄的有關“中西醫結閤治療類風濕關節炎”的隨機對照試驗進行檢索，應用Jadad量錶對納入的文獻報道進行評價、分析，併通過統計學軟件Review Manager 5.0對納入文獻實施薈萃分析。結果：共納入文獻12篇，病例總數為960例，採用中西醫結閤治療的500例類風濕關節炎患者為研究組，採用西醫治療的460例類風濕關節炎患者為對照組，薈萃分析顯示OR＝0.32，95% CI＝2.35～4.70，Z＝6.49，P<0.00001。結論：對類風濕關節炎患者實施中西醫結閤療法，顯著減少瞭單用西藥治療所引起的副反應情況，使用藥的耐受性明顯增彊，且治療總有效率顯著高于單用西藥治療，值得推廣應用。
목적：대중서의결합치료류풍습관절염적문헌진행회췌분석，위림상치료류풍습관절염제공의거。방법：대2008년1월-2014년1월유보、만방등수거고수록적유관“중서의결합치료류풍습관절염”적수궤대조시험진행검색，응용Jadad량표대납입적문헌보도진행평개、분석，병통과통계학연건Review Manager 5.0대납입문헌실시회췌분석。결과：공납입문헌12편，병례총수위960례，채용중서의결합치료적500례류풍습관절염환자위연구조，채용서의치료적460례류풍습관절염환자위대조조，회췌분석현시OR＝0.32，95% CI＝2.35～4.70，Z＝6.49，P<0.00001。결론：대류풍습관절염환자실시중서의결합요법，현저감소료단용서약치료소인기적부반응정황，사용약적내수성명현증강，차치료총유효솔현저고우단용서약치료，치득추엄응용。
Objective: To analyze clinical effect of TCM medicine on rheumatoid arthritis. Methods: A randomized controlled trial of retrieval was set by the Jadad scale evaluation and analysis of the reports of the included literature, and through statistical software Review Manager 5.0 of included studies carried out a meta-analysis. Results: Totally 12 literatures, a total of 960 cases, by the integrative medicine in 500 cases of rheumatoid arthritis patients as research group, by western medicine treatment for 460 cases of rheumatoid arthritis patients as control group; the meta-analysis indicates that OR=0.32, 95%CI=2.35~4.70, Z=6.49,P<0.00001. Conclusion: In patients with rheumatoid arthritis (RA) the implementation of integrative medicine combination therapy, can significantly reduce the side effects, drug tolerance significantly enhance; the total efficiency was significantly higher than that of the single western medicine treatment.
