中国药师
中國藥師
중국약사
CHINA PHARMACIST
2015年
8期
1284-1286
,共3页
马杰%孙焱%丁野%李文莉
馬傑%孫焱%丁野%李文莉
마걸%손염%정야%리문리
复方石淋通胶囊%绿原酸%薄层色谱法%高效液相色谱法
複方石淋通膠囊%綠原痠%薄層色譜法%高效液相色譜法
복방석림통효낭%록원산%박층색보법%고효액상색보법
Fufang Shilintong capsules%Chlorogenic%TLC%HPLC
目的：：修订提高复方石淋通胶囊的质量标准。方法：采用薄层色谱法鉴别处方中的忍冬藤、石韦；采用HPLC法测定处方中绿原酸的含量。结果：在TLC色谱中可检出忍冬藤、石韦药材的特征斑点,且斑点清晰,分离度好；绿原酸进样量在0.020~1.530μg(r=1.0000)范围内线性关系良好,平均加样回收率为99.2%,RSD=0.8%(n=6)。结论：所采用的方法准确、可靠,可行性及重复性良好,能更有效控制该制剂的质量。
目的：：脩訂提高複方石淋通膠囊的質量標準。方法：採用薄層色譜法鑒彆處方中的忍鼕籐、石韋；採用HPLC法測定處方中綠原痠的含量。結果：在TLC色譜中可檢齣忍鼕籐、石韋藥材的特徵斑點,且斑點清晰,分離度好；綠原痠進樣量在0.020~1.530μg(r=1.0000)範圍內線性關繫良好,平均加樣迴收率為99.2%,RSD=0.8%(n=6)。結論：所採用的方法準確、可靠,可行性及重複性良好,能更有效控製該製劑的質量。
목적：：수정제고복방석림통효낭적질량표준。방법：채용박층색보법감별처방중적인동등、석위；채용HPLC법측정처방중록원산적함량。결과：재TLC색보중가검출인동등、석위약재적특정반점,차반점청석,분리도호；록원산진양량재0.020~1.530μg(r=1.0000)범위내선성관계량호,평균가양회수솔위99.2%,RSD=0.8%(n=6)。결론：소채용적방법준학、가고,가행성급중복성량호,능경유효공제해제제적질량。
To modify and improve the quality standard of Fufang Shilintong capsules. Methods: Lonicerae Japonicae Caulis and Pyrrosoae Folium in Fufang Shilintong capsules were identified by TLC, and the content of chlorogenic in the capsules was determined by HPLC. Results: Specific spots of Lonicerae Japonicae Caulis and Pyrrosoae Folium were shown in TLC. Chlorogenic showed a good linear relationship within the range of 0. 020-1. 530 μg(r=1. 000 0), and the average recovery was 99. 2%(RSD=0. 8%, n=6). Conclusion:The method is accurate and reliable, which can be more effectively used in the quality control of Fufang Shilintong capsules.
