CAJ | 학술논문

牛支原体病是由牛支原体引起的，以肺炎、结膜炎、关节炎、中耳炎等为主要临床症状的疾病，世界范围内普遍存在。牛支原体的致病机理和毒力相关因子还不是很清楚，但有研究发现可变表面脂蛋白、黏附因子等可能与致病性相关。目前国内外用于确诊牛支原体病的主要方法包括病原体的分离鉴定、核酸诊断和血清学检测等；牛支原体疫苗被认为可以刺激机体产生可检测的IgM、IgG1、IgG2、和IgA等抗体反应。预防该病可通过加强牛群引进及饲养管理，对已发病牛群进行疫病控制与治疗等综合防控措施来实现。
우지원체병시유우지원체인기적，이폐염、결막염、관절염、중이염등위주요림상증상적질병，세계범위내보편존재。우지원체적치병궤리화독력상관인자환불시흔청초，단유연구발현가변표면지단백、점부인자등가능여치병성상관。목전국내외용우학진우지원체병적주요방법포괄병원체적분리감정、핵산진단화혈청학검측등；우지원체역묘피인위가이자격궤체산생가검측적IgM、IgG1、IgG2、화IgA등항체반응。예방해병가통과가강우군인진급사양관리，대이발병우군진행역병공제여치료등종합방공조시래실현。
Mycoplasma bovis disease is caused by Mycoplasma bovis, it can lead to pneumonia, conjunctivitis, arthritis, otitis media, etc., and exist all over the world. The pathogenesis and virulent related factors are not clear now, but it was reported that Vsp and adhesion factors may related with the pathogenesis. Currently, pathogen isolation, nucleic acid diagnosis and serologic test are used for diagnosis; vaccine is proved to induce IgM, IgG1, IgG2 and IgA for detecting antibody level. To prevent this diesease, it was suggested that, strengthen the introduction and management of cattle, control and therapy the diseased cattle are very important and helpful.