CAJ | 학술논문

昆虫尤其是完全变态昆虫的发育过程是一个复杂的网络调控过程，仍有很多问题尚待解决。miRNA是近年来发现的在真核生物中普遍存在的一类19~25 nt微小RNA分子，在转录后水平上发挥重要作用，广泛参与多种重要生物学过程。综述了近年来miRNA在调控完全变态昆虫(果蝇、家蚕、伊蚊、按蚊等)胚胎发育、组织分化以及变态发育等方面的研究进展，以期为深化理解昆虫变态发育机制、发现新的生物防控靶标分子奠定基础。
곤충우기시완전변태곤충적발육과정시일개복잡적망락조공과정，잉유흔다문제상대해결。miRNA시근년래발현적재진핵생물중보편존재적일류19~25 nt미소RNA분자，재전록후수평상발휘중요작용，엄범삼여다충중요생물학과정。종술료근년래miRNA재조공완전변태곤충(과승、가잠、이문、안문등)배태발육、조직분화이급변태발육등방면적연구진전，이기위심화리해곤충변태발육궤제、발현신적생물방공파표분자전정기출。
There are still many issues to be studied about the development of insects,especially complete metamorphosis insects,which is a complex network of regulatory processes. miRNA is present in eukaryotic cells and is a class of natural small regulatory RNA. Its size is 19—25 nucleotides. miRNAs play an important role in post-transcriptional gene regulation,and they can control hundreds of gene targets and regulate diverse biological processes. Here, we review recent developments of the roles of miRNAs in embryogenesis, tissue differentiation and metamorphosis of complete metamorphosis insects, such as drosophila,silkworm,aedes and anopheles,etc,in order to lay the foundation for profoundly reveal the metamorphosis developmental mechanism of insects and discover new molecular targets for prevention and control of insect pests.