CAJ | 학술논문

目的观察新辅助化疗合并腹腔镜直肠癌根治术对直肠癌治疗的效果.方法将78例直肠癌患者随机分为观察组和对照组,每组39例,分别采用新辅助化疗合并腹腔镜直肠癌根治术治疗和单纯腹腔镜直肠癌根治术治疗,比较两组患者的临床疗效.结果观察组根治性切除率(94.9%)高于对照组(82.1%)(P<0.05),术中出血量观察组较对照组少(P<0.05).两组患者局部复发率、3年生存率及远处转移率差异均有统计学意义(P<0.05).结论新辅助化疗合并腹腔镜直肠癌根治术对直肠癌治疗效果肯定,能提高根治性切除率,在降低术中出血量、减少复发、转移和延长生存期方面均有一定的优势.
목적 관찰신보조화료합병복강경직장암근치술대직장암치료적효과.방법장78례직장암환자수궤분위관찰조화대조조,매조39례,분별채용신보조화료합병복강경직장암근치술치료화단순복강경직장암근치술치료,비교량조환자적림상료효.결과 관찰조근치성절제솔(94.9%)고우대조조(82.1%)(P<0.05),술중출혈량관찰조교대조조소(P<0.05).량조환자국부복발솔、3년생존솔급원처전이솔차이균유통계학의의(P<0.05).결론 신보조화료합병복강경직장암근치술대직장암치료효과긍정,능제고근치성절제솔,재강저술중출혈량、감소복발、전이화연장생존기방면균유일정적우세.
Objective To evaluate the efficacy of neoadjuvant chemotherapy(NACT) combined with laparoscopic surgery in treating the colorectal cancer. Methods 78 patients with colorectal cancer were randomly divided into observation group and control group, each group of 39 cases, used NACT combined laparoscopic surgery and pure laparoscopic surgery, compared the clinical efficacy of two groups of patients.Results The radical resection rate of observation group was 94.9%, higher than the 82.1% of the control group(P<0.05);The intraoperative blood loss was less than the control group (P<0.05);Two groups of patients with local recurrence rate, 3 year survival rate and distant metastasis rate difference was statisticaly significant (P<0.05). Conclusion NACT and laparoscopic surgery for colorectal cancer patients was effective, and can improve the radical resection, reduce the bleeding reduce recurrence and metastasis and prolong the lifetime .