CAJ | 학술논문

目的研究脑桥梗死的危险因素、临床表现、神经影像学改变及预后.方法回顾性分析100例脑桥梗死患者的临床资料, 包括:高危因素、临床表现、影像学检查及预后.结果高危因素:高脂血症、高血压、糖尿病、吸烟.主要病因为动脉粥样硬化.主要临床特点:眩晕、病灶对侧的中枢性面瘫和肢体瘫痪、构音障碍、偏身麻木、球麻痹、眼震、复视、意识障碍等.按照头颅磁共振成像(MRI)横轴位上的病灶位置, 腹内侧梗死49例, 腹外侧梗死31例, 被盖部梗死13例, 双侧梗死7例.腹内、外侧梗死起病后30 d后神经功能缺失症状较前好转, 差异具有统计学意义(P<0.01).双侧脑桥梗死改良Rankin量表(mRS)评分较其余各组高, 差异具有统计学意义 (P<0.05).结论动脉粥样硬化是脑桥梗死患者最常见的病因, 眩晕、感觉运动障碍、构音障碍、球麻痹是常见的临床特点, 脑桥梗死病灶多位于腹侧, 不同部位范围影响患者预后.
목적 연구뇌교경사적위험인소、림상표현、신경영상학개변급예후.방법 회고성분석100례뇌교경사환자적림상자료, 포괄:고위인소、림상표현、영상학검사급예후.결과 고위인소:고지혈증、고혈압、당뇨병、흡연.주요병인위동맥죽양경화.주요림상특점:현훈、병조대측적중추성면탄화지체탄탄、구음장애、편신마목、구마비、안진、복시、의식장애등.안조두로자공진성상(MRI)횡축위상적병조위치, 복내측경사49례, 복외측경사31례, 피개부경사13례, 쌍측경사7례.복내、외측경사기병후30 d후신경공능결실증상교전호전, 차이구유통계학의의(P<0.01).쌍측뇌교경사개량Rankin량표(mRS)평분교기여각조고, 차이구유통계학의의 (P<0.05).결론 동맥죽양경화시뇌교경사환자최상견적병인, 현훈、감각운동장애、구음장애、구마비시상견적림상특점, 뇌교경사병조다위우복측, 불동부위범위영향환자예후.
Objective To research risk factor, clinical manifestation, neuroimaging change and prognosis of pontine infarction.Methods A retrospective analysis was made on clinical data, including high risk factor, clinical manifestation, imaging examination and prognosis, of 100 patients with pontine infarction.Results High risk factors included hyperlipidaemia, hypertension, diabetes mellitus, and smoking. Atherosclerosis was the main pathogenesis. Main clinical manifestations included dizziness, central facial paralysis and acroparalysis in opposite of lesion, dysarthria, hemianesthesia, bulbar paralysis, nystagmus, diplopia, and disturbance of consciousness. Transverse lesion location of brain magnetic resonance imaging(MRI) showed 49 cases in ventromedial infarction group, 31 cases in ventrolateral infarcts group, 13 cases in tegmentum infraction group, and 7 cases in bilateral infarction group. Neurologic deficit symptoms were improved after 30 d of ventromedial and ventrolateral infarction onset, and the difference had statistical significance (P<0.01). Bilateral infarction group had higher modified Rankin scale (mRS) score than the other groups, and their difference had statistical significance (P<0.05). Conclusion Atherosclerosis is the main pathogenesis of pontine infarction patients. Dizziness, sensorimotor dysfunction, dysarthria, and bulbar paralysis are common clinical manifestations. Ventral branches are main onset location of pontine infarction. Different locations influence their prognosis.