中国处方药
中國處方藥
중국처방약
CHINA PRESCRIPTION DRUG
2015年
8期
63-64
,共2页
氨氯地平%贝那普利%高血压%脑卒中
氨氯地平%貝那普利%高血壓%腦卒中
안록지평%패나보리%고혈압%뇌졸중
Amlodipine%Benazepril%Hypertension%Stroke
目的 对比研究氨氯地平与贝那普利治疗高血压脑卒中的临床疗效及复发情况.方法 选择150例高血压脑卒中患者进行研究,按入组前后顺序分为试验组和对照组.试验组75例患者给予氨氯地平治疗,对照组75例患者给予贝那普利治疗.治疗持续2~24个月,平均18个月,治疗后对两组患者血压水平及脑卒中复发情况进行比较分析.结果 经不同治疗后,两组患者收缩压及舒张压较治疗前均降低(P均<0.05),试验组收缩压及舒张压与对照组比较无差异(P均>0.05);试验组脑卒中复发率为13.3%,低于对照组的26.7%,两组比较有统计学差异(χ2=4.166 7,P=0.041 2).结论 在高血压脑卒中的治疗中,氨氯地平与贝那普利均具有良好的降压效果,但氨氯地平对预防脑卒中的复发效果较好.
目的 對比研究氨氯地平與貝那普利治療高血壓腦卒中的臨床療效及複髮情況.方法 選擇150例高血壓腦卒中患者進行研究,按入組前後順序分為試驗組和對照組.試驗組75例患者給予氨氯地平治療,對照組75例患者給予貝那普利治療.治療持續2~24箇月,平均18箇月,治療後對兩組患者血壓水平及腦卒中複髮情況進行比較分析.結果 經不同治療後,兩組患者收縮壓及舒張壓較治療前均降低(P均<0.05),試驗組收縮壓及舒張壓與對照組比較無差異(P均>0.05);試驗組腦卒中複髮率為13.3%,低于對照組的26.7%,兩組比較有統計學差異(χ2=4.166 7,P=0.041 2).結論 在高血壓腦卒中的治療中,氨氯地平與貝那普利均具有良好的降壓效果,但氨氯地平對預防腦卒中的複髮效果較好.
목적 대비연구안록지평여패나보리치료고혈압뇌졸중적림상료효급복발정황.방법 선택150례고혈압뇌졸중환자진행연구,안입조전후순서분위시험조화대조조.시험조75례환자급여안록지평치료,대조조75례환자급여패나보리치료.치료지속2~24개월,평균18개월,치료후대량조환자혈압수평급뇌졸중복발정황진행비교분석.결과 경불동치료후,량조환자수축압급서장압교치료전균강저(P균<0.05),시험조수축압급서장압여대조조비교무차이(P균>0.05);시험조뇌졸중복발솔위13.3%,저우대조조적26.7%,량조비교유통계학차이(χ2=4.166 7,P=0.041 2).결론 재고혈압뇌졸중적치료중,안록지평여패나보리균구유량호적강압효과,단안록지평대예방뇌졸중적복발효과교호.
Objective To compare the efficacy and recurrence rate of amlodipine and benazeprilthe in the treatment of hypertensive stroke.Methods 150 patients of hypertensive stroke were studied and divided into test group and control group according to the order. 75 cases in the test group were given amlodipine treatment, and 75 cases in the control group were treated with benazepril. After treatment, which lasted 2 to 24 months with an average of 18 months,blood pressure and stroke recurrence of two groups were compared.Results After treatment, systolic and diastolic blood pressure of two groups were significantly decreased(P<0.05). The systolic and diastolic blood pressure of test group and control group were not significantly different(allP>0.05); stroke recurrence rate of test group was 13.3%, significantly lower than the control group(26.7%). there were significant differences(χ2= 4.1667,P= 0.0412) .Conclusion In the treatment of hypertensive stroke, amlodipine and benazepril make similar antihypertensive effect, but amlodipine have significant preventive effect of stroke recurrence.
