中国处方药
中國處方藥
중국처방약
CHINA PRESCRIPTION DRUG
2015年
8期
1-3
,共3页
梁子安%马春成%禤晓燕%李杰峰%伍劲华%杨爱成
樑子安%馬春成%禤曉燕%李傑峰%伍勁華%楊愛成
량자안%마춘성%훤효연%리걸봉%오경화%양애성
血液透析%肠外营养%50％葡萄糖%8.5％氨基酸%20％中/长链脂肪乳
血液透析%腸外營養%50％葡萄糖%8.5％氨基痠%20％中/長鏈脂肪乳
혈액투석%장외영양%50％포도당%8.5％안기산%20％중/장련지방유
Maintenance hemodialysis%Parenteral nutrition%50％ glucose%8.5％ amino acid%20％ medium/ long-chain fat emulsion
目的 探讨通过肠外营养提高能量供给对维持血液透析患者营养状况的影响.方法 按标准纳入2013年1月~2014年9月期间就诊进行维持性血液透析治疗的60例患者,随机分为对照组和试验组,每组患者30例.对照组干预方法:充分透析、积极纠正酸中毒、常规饮食教育、口服营养干预等;试验组干预:除充分透析和积极纠正酸中毒外,每次血液透析过程中给予250 mL 50%葡萄糖注射液,500 mL 8.5% 氨基酸注射液和20%中/长链脂肪乳注射液250 mL,记录患者治疗前后的血清白蛋白、血清前蛋白、血清转铁蛋白、蛋白分解率(PCR)、胆固醇、尿素氮、肌酐、C反应蛋白等指标.结果 两组患者的胆固醇、尿素氮、肌酐、C反应蛋白等方面治疗前后比较,差异均无统计学意义(P>0.05).对照组的血清前蛋白、血清转铁蛋白、PCR经充分透析、积极纠正酸中毒、常规饮食教育和口服营养干预后都稍有提高,但差异无统计学意义(P>0.05);而试验组的血清白蛋白、血清前蛋白、血清转铁蛋白、PCR在肠外营养干预后水平均高于干预前,且差异均有统计学意义(P<0.05).结论 通过肠外营养提高能量供给能够有效地改善维持血液透析患者的营养状况,安全有效.
目的 探討通過腸外營養提高能量供給對維持血液透析患者營養狀況的影響.方法 按標準納入2013年1月~2014年9月期間就診進行維持性血液透析治療的60例患者,隨機分為對照組和試驗組,每組患者30例.對照組榦預方法:充分透析、積極糾正痠中毒、常規飲食教育、口服營養榦預等;試驗組榦預:除充分透析和積極糾正痠中毒外,每次血液透析過程中給予250 mL 50%葡萄糖註射液,500 mL 8.5% 氨基痠註射液和20%中/長鏈脂肪乳註射液250 mL,記錄患者治療前後的血清白蛋白、血清前蛋白、血清轉鐵蛋白、蛋白分解率(PCR)、膽固醇、尿素氮、肌酐、C反應蛋白等指標.結果 兩組患者的膽固醇、尿素氮、肌酐、C反應蛋白等方麵治療前後比較,差異均無統計學意義(P>0.05).對照組的血清前蛋白、血清轉鐵蛋白、PCR經充分透析、積極糾正痠中毒、常規飲食教育和口服營養榦預後都稍有提高,但差異無統計學意義(P>0.05);而試驗組的血清白蛋白、血清前蛋白、血清轉鐵蛋白、PCR在腸外營養榦預後水平均高于榦預前,且差異均有統計學意義(P<0.05).結論 通過腸外營養提高能量供給能夠有效地改善維持血液透析患者的營養狀況,安全有效.
목적 탐토통과장외영양제고능량공급대유지혈액투석환자영양상황적영향.방법 안표준납입2013년1월~2014년9월기간취진진행유지성혈액투석치료적60례환자,수궤분위대조조화시험조,매조환자30례.대조조간예방법:충분투석、적겁규정산중독、상규음식교육、구복영양간예등;시험조간예:제충분투석화적겁규정산중독외,매차혈액투석과정중급여250 mL 50%포도당주사액,500 mL 8.5% 안기산주사액화20%중/장련지방유주사액250 mL,기록환자치료전후적혈청백단백、혈청전단백、혈청전철단백、단백분해솔(PCR)、담고순、뇨소담、기항、C반응단백등지표.결과 량조환자적담고순、뇨소담、기항、C반응단백등방면치료전후비교,차이균무통계학의의(P>0.05).대조조적혈청전단백、혈청전철단백、PCR경충분투석、적겁규정산중독、상규음식교육화구복영양간예후도초유제고,단차이무통계학의의(P>0.05);이시험조적혈청백단백、혈청전단백、혈청전철단백、PCR재장외영양간예후수평균고우간예전,차차이균유통계학의의(P<0.05).결론 통과장외영양제고능량공급능구유효지개선유지혈액투석환자적영양상황,안전유효.
Objective To explore the value of parenteral nutrition on nutritional status of patients with maintenance hemodialysis.Methods Patients are randomly divided into control group and experience group with 300 cases in each group. Control group: adequate dialysis, correction of acidosis, regular diet education, oral nutrition intervention and so on; Experimental group: in addition to the adequate dialysis and correction of acidosis, 250 ml 50% glucose, 500 ml of 8.5% amino acid and 250 ml 20% medium/ long-chain fat emulsion was injected to patient in the process of hemodialysis. It is vital to record patients' serum albumin, serum preprotein, serum transferrin, standardized protein decomposition rate(PCR), cholesterol, urea nitrogen, creatinine, c-reactive protein and so on before and after treatment.Results Index of two groups of patients with cholesterol, urea nitrogen, creatinine, and c-reactive protein were no statistically significant difference between before treatment and after treatment(P>0.05).Compare with after treatment, the clinical index of serum albumin, serum protein and serum transferrin, protein decomposition rate(PCR)of control group had a slightly increase, but no statistical significance(P>0.05); However, experimental group had a higher level which had statistical significance(P<0.05).Conclusion It is safe and effective to improve the nutritional status of maintenance hemodialysis patients through parenteral nutrition.
