CAJ | 학술논문

目的：探讨盐酸山莨菪碱配伍缩宫素对缩短产程的作用。方法将100例活跃期延长产妇随机分为两组，各50例。对照组在活跃期延长后单用缩宫素，观察组在此基础上联合使用盐酸山莨菪碱，比较两组产妇宫颈成熟度评分、产程时间、分娩方式、产后出血及新生儿情况。结果观察组宫颈成熟度评分高于对照组，差异有统计学意义（P ﹤0.05）；自活跃期开始，观察组活跃期、第二产程、第三产程及总产程时间均短于对照组，差异有统计学意义（ P ﹤0.05）；观察组剖宫产率为20.00%，低于对照组，差异有统计学意义（P ﹤0.05）；观察组产妇产后24 h 出血量为（176.2±5.3）mL，低于对照组，差异有统计学意义（P ﹤0.05）；观察组新生儿出生后5 min Apgar 评分为（9.3±0.5）分，高于对照组，差异有统计学意义（P ﹤0.05）。结论对活跃期延长的产妇应用盐酸山莨菪碱配伍缩宫素可加速宫口扩张，缩短产程，有利于改善产妇及新生儿预后。
목적：탐토염산산랑탕감배오축궁소대축단산정적작용。방법장100례활약기연장산부수궤분위량조，각50례。대조조재활약기연장후단용축궁소，관찰조재차기출상연합사용염산산랑탕감，비교량조산부궁경성숙도평분、산정시간、분면방식、산후출혈급신생인정황。결과관찰조궁경성숙도평분고우대조조，차이유통계학의의（P ﹤0.05）；자활약기개시，관찰조활약기、제이산정、제삼산정급총산정시간균단우대조조，차이유통계학의의（ P ﹤0.05）；관찰조부궁산솔위20.00%，저우대조조，차이유통계학의의（P ﹤0.05）；관찰조산부산후24 h 출혈량위（176.2±5.3）mL，저우대조조，차이유통계학의의（P ﹤0.05）；관찰조신생인출생후5 min Apgar 평분위（9.3±0.5）분，고우대조조，차이유통계학의의（P ﹤0.05）。결론대활약기연장적산부응용염산산랑탕감배오축궁소가가속궁구확장，축단산정，유리우개선산부급신생인예후。
Objective To investigate the effect of anisodamine combined with oxytocin on shortening the birth process. Methods 100 cases of maternals with prolonged active phase ever treated in our hospital were randomly divided into two groups,with 50 cases in each group. After the prolonged active phase was diagnosed,maternals in the study group were treated with anisodamine combined with oxytocin, whereas maternals in the control group treated with oxytocin alone. The maternal cervical maturity score,duration of labor,mode of delivery, postpartum hemorrhage and incidence of neonatal asphyxia between the two groups were compared. Results The maternal cervical maturity score in the study group was significantly higher than that in the control group(P ﹤ 0. 05). Duration of the active phase,the second labor stage,the third labor stage and the total labor stage in the study group were shorter than those in the control group,and the differences were statistically significant(P ﹤ 0. 01). The cesarean section rate of the study group was 20. 00% ,significantly lower than that of the control group(P ﹤ 0. 01),and the 24h postpartum hemorrhage of the study group was(176. 2 ± 5. 3)ml,also significantly lower than that of the control group(P ﹤ 0. 01). But the 5 min Apgar score after birth of the study group was(9. 3 ± 0. 6)points,significantly higher than that of the control group,with significant difference between the two groups(P ﹤ 0. 01). Conclusion Application of anisodamine combined with oxytocin for active phase prolonged maternals could accelerate cervical dilation and shorten birth process,as to improve maternal and neonatal outcomes,and should be widely promoted.