大理学院学报
大理學院學報
대이학원학보
JOURNAL OF DALI COLLEGE
2015年
8期
18-21
,共4页
非酒精性脂肪肝%急性冠脉综合征%颈动脉斑块
非酒精性脂肪肝%急性冠脈綜閤徵%頸動脈斑塊
비주정성지방간%급성관맥종합정%경동맥반괴
non-alcoholic fatty liver disease%acute coronary syndrome coronary heart disease%carotid artery plaque
目的：探讨非酒精性脂肪肝（NAFLD）与冠心病急性冠脉综合征（ACS）发病的关系。方法：收集2006年1月至2013年12月因ACS住院的患者140例，将所有患者是否合并NAFLD分为NAFLD组（n=80）及非NAFLD组（n=60），通过血管超声结果比较两组颈动脉斑块检出率。并将ACS分为3个临床亚组不稳定型心绞痛（UA）、急性ST段抬高心肌梗塞（STEMI）、急性非ST段抬高心肌梗塞（NSTEMI），观察各亚组与NAFLD发病率有无差异性。比较NAFLD组和非NAFLD组甘油三酯（TG）、胆固醇（TC）、低密度脂蛋白（LDL-C）的水平有无差异性。结果：ACS合并NAFLD组颈动脉斑块检出率明显高于非NAFLD组（85%vs 40%），两组比较差异有统计学意义（P<0.01）；ACS 3个亚组NAFLD发病率与非NAFLD发病率差异无统计学意义（P>0.05）；NAFLD组TG、TC、LDL-C水平明显高于非NAFLD组（P<0.05）。结论：NAFLD患者存在出现颈动脉斑块及高脂血症的高风险，是冠心病ACS的潜在危险因素，及时干预NAFLD患者可以在防治心血管疾病方面获益。
目的：探討非酒精性脂肪肝（NAFLD）與冠心病急性冠脈綜閤徵（ACS）髮病的關繫。方法：收集2006年1月至2013年12月因ACS住院的患者140例，將所有患者是否閤併NAFLD分為NAFLD組（n=80）及非NAFLD組（n=60），通過血管超聲結果比較兩組頸動脈斑塊檢齣率。併將ACS分為3箇臨床亞組不穩定型心絞痛（UA）、急性ST段抬高心肌梗塞（STEMI）、急性非ST段抬高心肌梗塞（NSTEMI），觀察各亞組與NAFLD髮病率有無差異性。比較NAFLD組和非NAFLD組甘油三酯（TG）、膽固醇（TC）、低密度脂蛋白（LDL-C）的水平有無差異性。結果：ACS閤併NAFLD組頸動脈斑塊檢齣率明顯高于非NAFLD組（85%vs 40%），兩組比較差異有統計學意義（P<0.01）；ACS 3箇亞組NAFLD髮病率與非NAFLD髮病率差異無統計學意義（P>0.05）；NAFLD組TG、TC、LDL-C水平明顯高于非NAFLD組（P<0.05）。結論：NAFLD患者存在齣現頸動脈斑塊及高脂血癥的高風險，是冠心病ACS的潛在危險因素，及時榦預NAFLD患者可以在防治心血管疾病方麵穫益。
목적：탐토비주정성지방간（NAFLD）여관심병급성관맥종합정（ACS）발병적관계。방법：수집2006년1월지2013년12월인ACS주원적환자140례，장소유환자시부합병NAFLD분위NAFLD조（n=80）급비NAFLD조（n=60），통과혈관초성결과비교량조경동맥반괴검출솔。병장ACS분위3개림상아조불은정형심교통（UA）、급성ST단태고심기경새（STEMI）、급성비ST단태고심기경새（NSTEMI），관찰각아조여NAFLD발병솔유무차이성。비교NAFLD조화비NAFLD조감유삼지（TG）、담고순（TC）、저밀도지단백（LDL-C）적수평유무차이성。결과：ACS합병NAFLD조경동맥반괴검출솔명현고우비NAFLD조（85%vs 40%），량조비교차이유통계학의의（P<0.01）；ACS 3개아조NAFLD발병솔여비NAFLD발병솔차이무통계학의의（P>0.05）；NAFLD조TG、TC、LDL-C수평명현고우비NAFLD조（P<0.05）。결론：NAFLD환자존재출현경동맥반괴급고지혈증적고풍험，시관심병ACS적잠재위험인소，급시간예NAFLD환자가이재방치심혈관질병방면획익。
Objective:To study the correlation of non-alcoholic fatty liver disease(NAFLD)and acute coronary syndrome(ACS) pathogenesis. Methods:One hundred and forty cases of ACS with NAFLD hospitalized in our hospital from January 2006 to December 2013 were divided into NAFLD group (n=80) and non NAFLD group (n=60), the results were compared by vascular ultrasound detection rate of carotid plaque. ACS was divided into three clinical subgroups of unstable angina pectoris (UA), acute ST segment elevation myocardial infarction (STEMI), non ST segment elevation acute myocardial infarction (NSTEMI). And the incidence of NAFLD was observed in each subgroup. Riglyceride (TG), cholesterol (TC), low density lipoprotein (LDL-C) levers have no difference in both NAFLD group and non NAFLD group. Results:The detection rate of carotid plaque in ACS combined with NAFLD group was significantly higher than that in non NAFLD group(85%vs 40%), there was significant difference between two groups(P<0.01); there was no statistically significant in the three subgroups of ACS the incidence of NAFLD and non NAFLD incidence rate difference (P>0.05); group NAFLD, TG, TC, LDL-C level was significantly higher than that of non NAFLD group (P<0.05). Conclusion: NAFLD patients have high risk carotid atherosclerosis and hyperlipidemia appears, which is a potential risk factor for coronary heart disease ACS, timely intervention of NAFLD patients can be benefit in the prevention and treatment of cardiovascular diseases.
