临床精神医学杂志
臨床精神醫學雜誌
림상정신의학잡지
JOURNAL OF CLINICAL PSYCHOLOGICAL MEDICINE
2015年
4期
263-265
,共3页
王智雄%边云%朱瑜%吴承京%陈丽
王智雄%邊雲%硃瑜%吳承京%陳麗
왕지웅%변운%주유%오승경%진려
精神分裂症%睡眠结构%多导睡眠图%镇静催眠药物
精神分裂癥%睡眠結構%多導睡眠圖%鎮靜催眠藥物
정신분렬증%수면결구%다도수면도%진정최면약물
schizophrenia%sleep structure%polysomnography%sedative hypnotic drugs
目的:探讨稳定期精神分裂症患者睡眠结构特点及其影响因素。方法:采用随机整群抽样方法,对114例稳定期精神分裂症患者进行多导睡眠图(PSG)检查,分析睡眠结构及其影响因素。结果:入组患者睡眠潜伏期平均为47 min,睡眠时间约5.5 h,睡眠效率66.14%。Ⅰ~Ⅳ期及快动眼(REM)期睡眠分别占总睡眠19.31%、57.68%、1.17%、1.02%及20.83%。睡眠效率正常24例(21.1%),Ⅲ期睡眠缺如42例(36.8%),Ⅳ期睡眠缺如90例(78.9%),REM 期睡眠缺如6例(5.3%)。Logistic 回归分析显示镇静催眠药物对于Ⅳ期睡眠的影响具有统计学意义(P ﹤0.05)。结论:稳定期精神分裂症患者睡眠效率下降,浅睡眠增多,深睡眠减少;镇静催眠药可有效改善患者的睡眠结构。
目的:探討穩定期精神分裂癥患者睡眠結構特點及其影響因素。方法:採用隨機整群抽樣方法,對114例穩定期精神分裂癥患者進行多導睡眠圖(PSG)檢查,分析睡眠結構及其影響因素。結果:入組患者睡眠潛伏期平均為47 min,睡眠時間約5.5 h,睡眠效率66.14%。Ⅰ~Ⅳ期及快動眼(REM)期睡眠分彆佔總睡眠19.31%、57.68%、1.17%、1.02%及20.83%。睡眠效率正常24例(21.1%),Ⅲ期睡眠缺如42例(36.8%),Ⅳ期睡眠缺如90例(78.9%),REM 期睡眠缺如6例(5.3%)。Logistic 迴歸分析顯示鎮靜催眠藥物對于Ⅳ期睡眠的影響具有統計學意義(P ﹤0.05)。結論:穩定期精神分裂癥患者睡眠效率下降,淺睡眠增多,深睡眠減少;鎮靜催眠藥可有效改善患者的睡眠結構。
목적:탐토은정기정신분렬증환자수면결구특점급기영향인소。방법:채용수궤정군추양방법,대114례은정기정신분렬증환자진행다도수면도(PSG)검사,분석수면결구급기영향인소。결과:입조환자수면잠복기평균위47 min,수면시간약5.5 h,수면효솔66.14%。Ⅰ~Ⅳ기급쾌동안(REM)기수면분별점총수면19.31%、57.68%、1.17%、1.02%급20.83%。수면효솔정상24례(21.1%),Ⅲ기수면결여42례(36.8%),Ⅳ기수면결여90례(78.9%),REM 기수면결여6례(5.3%)。Logistic 회귀분석현시진정최면약물대우Ⅳ기수면적영향구유통계학의의(P ﹤0.05)。결론:은정기정신분렬증환자수면효솔하강,천수면증다,심수면감소;진정최면약가유효개선환자적수면결구。
Objective:To explore the sleep structure characteristics and its effect factors in stable state pa-tients with schizophrenia. Method:Using random cluster sampling method,polysomnography(PSG)examina-tion was performed in 114 stable state patients with schizophrenia. The sleep structure and its effect factors were analyzed. Results:The average time from lights-off to sleep in patients was 47 min,the average sleep time was 5. 5 h,the sleep efficiency was 66. 14% . The distribution of stagesⅠto Ⅳ and rapid eye movement(REM)in total sleep time were 19. 31% ,57. 68% ,1. 17% ,1. 02% and 20. 83% . Only 24(21. 1% )cases had normal sleep effi-ciency. Forty-two(36. 8% )cases had sleep absence in stage III,90(78. 9% )cases with sleep absence in stageⅣ,6(5. 3% )cases with sleep absence in stage of rapid eye movement(REM). Logistic regression analysis showed that the odds ratio of sedative hypnotic drugs effect on sleep stage Ⅳ was 5. 70(95% CI:1. 22 -26. 57). Conclusion:The sleep efficiency is reduced in schizophrenia patients,the stage of shallow sleep is increased and deep sleep is decreased. Sedative hypnotics can effectively improve the patientˊs sleep structure.