CAJ | 학술논문

目的:探讨独活寄生汤加减内服外洗治疗老年退行性膝关节骨性关节炎的临床疗效.方法:选取我院2010年11月-2014年11月老年退行性膝关节骨性关节炎患者72例,随机分为对照组和治疗组.治疗组采用独活寄生汤加减内服外洗治疗,实验组采用双氯芬酸钠缓释片口服治疗.比较两组患者膝关节骨性关节炎疼痛功能指数评分、治疗疗效以及各期的平均治愈率.结果:比较两组患者膝关节骨性关节炎疼痛功能指数评分,发现治疗后4周疼痛功能指数评分明显降低,两组患者的病情均有明显改善,治疗组较对照组降低更为明显;停药后4周疼痛功能指数评分略有上升但不明显,对照组较治疗组上升明显.两组患者治疗疗效比较,治愈和有效差异显著(P<0.05);显效和无效差异不显著(P>0.05);总有效率分别为91.7%和86.1%,差异不显著(P>0.05).比较两组患者各期的平均治愈率,发现1期的治愈率最高,分别为44.4%和40.0%;2期、3期和4期治愈率比1期低;5期治愈率为0.0%.结论:独活寄生汤加减内服外洗治疗老年退行性膝关节骨性关节炎能降低膝关节骨性关节炎疼痛功能指数评分,提高临床疗效,具有临床推广和应用价值.
목적:탐토독활기생탕가감내복외세치료노년퇴행성슬관절골성관절염적림상료효.방법:선취아원2010년11월-2014년11월노년퇴행성슬관절골성관절염환자72례,수궤분위대조조화치료조.치료조채용독활기생탕가감내복외세치료,실험조채용쌍록분산납완석편구복치료.비교량조환자슬관절골성관절염동통공능지수평분、치료료효이급각기적평균치유솔.결과:비교량조환자슬관절골성관절염동통공능지수평분,발현치료후4주동통공능지수평분명현강저,량조환자적병정균유명현개선,치료조교대조조강저경위명현;정약후4주동통공능지수평분략유상승단불명현,대조조교치료조상승명현.량조환자치료료효비교,치유화유효차이현저(P<0.05);현효화무효차이불현저(P>0.05);총유효솔분별위91.7%화86.1%,차이불현저(P>0.05).비교량조환자각기적평균치유솔,발현1기적치유솔최고,분별위44.4%화40.0%;2기、3기화4기치유솔비1기저;5기치유솔위0.0%.결론:독활기생탕가감내복외세치료노년퇴행성슬관절골성관절염능강저슬관절골성관절염동통공능지수평분,제고림상료효,구유림상추엄화응용개치.
Objective: Clinical efficacy of the Duhuo Jisheng decoction was investigated for knee degenerative osteoarthritis. Methods: 72 cases of degenerative osteoarthritis were randomly divided into control and treatment groups. The treatment group received oral the Duhuo Jisheng decoction; The contol group took sustained-release tablets of diclofenac sodium. Results: For 4 weeks the treatment pain functional index score was significantly lower in the treatment group significantly; 4 weeks later, pain functional index score rose slightly but not significantly. Curing and effective are significant difference (P<0.05); markedly and invalid were not significant (P>0.05); the total efficiency was 91.7% and 86.1% respectively; the difference was not significant (P>0.05). Conclusion: Internal and external treatment of degenerative osteoarthritis with the Duhuo Jisheng decoction can reduce the pain functional index scores, improve the clinical efficacy.