CAJ | 학술논문

目的：探讨子宫内膜癌术中冰冻和术后石蜡病理诊断符合率及其影响因素。方法选取2013年7月～2014年7月来我院就诊的术前病理诊断为子宫内膜癌患者75例，观察及比较采用术中冰冻切片和术后石蜡切片病理诊断子宫内膜癌患者的细胞级别和病变肌层浸润深度指标。结果随着组织级别增加，术中冰冻切片与术后石蜡病理诊断符合率增加。Ⅰ级、Ⅱ级、Ⅲ级术中冰冻切片与术后石蜡病理诊断病变肌层浸润深度的符合率依次为32.14%、86.05%和100.00%，差异有统计学意义（P＜0.05）。术中冰冻与术后石蜡病理比较，绝经后子宫内膜癌患者和X线钼靶多发钙化点减少，其判断组织学级别的准确性明显提高（P＜0.05）。结论冰冻病理在诊断子宫内膜癌肌层浸润深度上符合率较高，但在细胞级别的诊断上有一定局限。
목적：탐토자궁내막암술중빙동화술후석사병리진단부합솔급기영향인소。방법선취2013년7월～2014년7월래아원취진적술전병리진단위자궁내막암환자75례，관찰급비교채용술중빙동절편화술후석사절편병리진단자궁내막암환자적세포급별화병변기층침윤심도지표。결과수착조직급별증가，술중빙동절편여술후석사병리진단부합솔증가。Ⅰ급、Ⅱ급、Ⅲ급술중빙동절편여술후석사병리진단병변기층침윤심도적부합솔의차위32.14%、86.05%화100.00%，차이유통계학의의（P＜0.05）。술중빙동여술후석사병리비교，절경후자궁내막암환자화X선목파다발개화점감소，기판단조직학급별적준학성명현제고（P＜0.05）。결론빙동병리재진단자궁내막암기층침윤심도상부합솔교고，단재세포급별적진단상유일정국한。
ObjectiveTo explore the diagnostic coincidence rate and influencing factors of intraoperative biopsy and postoperative paraffin pathology in endometrial carcinoma.Methods75 cases with preoperative pathological diagnosis of endometrial carcinoma from 2013 July to 2014 July in our hospital were selected, and the intraoperative biopsy and postoperative paraffin pathology were observed and compared on the cellular level and depth of myometrial invasion in patients with endometrial carcinoma.Results As the organization level increase, the diagnostic coincidence rate of intraoperative biopsy and postoperative paraffin pathology increase.In the diagnosis of depth of myometrial invasion, the diagnosis coincidence rate of grade I, II and III by intraoperative biopsy and postoperative paraffin pathology was 32.14%, 86.05% and 100.00%, the difference was statistically significant (P<0.05). Compared with postoperative paraffin pathology,the number of post-menopause endometrial carcinoma patients and multiple calcification by X-ray molybdenum target reduced by intraoperative biopsy, the accuracy of judging histological grade enhanced(P<0.05).Conclusion The coincidence rate of depth of myometrial invasion in endometrial carcinoma by intraoperative biopsy pathology is high, but there is certain limitationin in the diagnosis of cellular level.