CAJ | 학술논문

目的探讨利奈唑胺治疗耐甲氧西林金黄色葡萄球菌呼吸机相关性肺炎的临床疗效。方法30例诊断为耐甲氧西林金黄色葡萄球菌所致呼吸机相关性肺炎的患者根据住院单双号顺序分为各15例的研究组和对照组，研究组接受利奈唑胺治疗，对照组接受万古霉素治疗。结果研究组和对照组治疗前血白细胞、超敏 C 反应蛋白、降钙素原结果比较无差异（P ＞0.05），治疗后有差异（P ＜0.05）；研究组和对<br>　　照组治疗的总有效率分别为73.3%和60.0%，差异具有统计学意义（P＜0.05）。结论利奈唑胺治疗耐甲氧西林金黄色葡萄球菌呼吸机相关性肺炎疗效肯定。
목적탐토리내서알치료내갑양서림금황색포도구균호흡궤상관성폐염적림상료효。방법30례진단위내갑양서림금황색포도구균소치호흡궤상관성폐염적환자근거주원단쌍호순서분위각15례적연구조화대조조，연구조접수리내서알치료，대조조접수만고매소치료。결과연구조화대조조치료전혈백세포、초민 C 반응단백、강개소원결과비교무차이（P ＞0.05），치료후유차이（P ＜0.05）；연구조화대<br>　　조조치료적총유효솔분별위73.3%화60.0%，차이구유통계학의의（P＜0.05）。결론리내서알치료내갑양서림금황색포도구균호흡궤상관성폐염료효긍정。
Objective To discuss the clinical efficacy of linezolid in treatment of ventilator-associated pneumonia with meticillin-resistant staphylococcus aureus. Methods 30 patients diagnosed ventilator-associated pneumonia with meticillin-resistant staphylococcus aureus were divided into study group and control group according to hospitalization single and double, 15 cases in each group. Study group received linezolid while control group received vancomycin. Results There had no difference in the results of white blood cell and C reactive protein between two groups before treatment (P>0.05), while after treatment there had (P<0.05). The total effective rate of study group and control group were 73.3% and 60%, differences had statistical significance (P<0.05). Conclusion Linezolid in treatment of ventilator-associated pneumonia with meticillin-resistant staphylococcus aureus has curative effect.