中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2015年
12期
31-33
,共3页
高血压%冠心病%拉西地平%阿托伐他汀钙
高血壓%冠心病%拉西地平%阿託伐他汀鈣
고혈압%관심병%랍서지평%아탁벌타정개
Hypertension%Coronary heart disease%Lacidipine%Atorvastatin calcium
目的：探讨拉西地平联合阿托伐他汀钙治疗高血压合并冠心病患者的临床效果。方法选择2014年1月～2015年2月于我院确诊为高血压合并冠心病患者94例作为研究对象，根据治疗药物不同分为治疗组（56例）和对照组（38例），对照组采用硝苯地平控释片治疗，治疗组采用拉西地平联合阿托伐他汀钙联合治疗，比较两组患者治疗后的血压、血脂水平的变化等临床疗效。结果与对照组比较治疗组治疗总有效率明显较高，两组差异有统计学意义（P＜0.05）。治疗后两组患者收缩压、舒张压、三酰甘油、总胆固醇水平等均明显低于治疗前，但治疗后治疗组各指标水平改善水平优于对照组，两组差异有统计学意义（P＜0.05）。结论拉西地平与阿托伐他汀钙联合用药治疗高血压合并冠心病能够起到协同增效的作用，可以有效控制患者的血压水平，并改善患者血脂情况，安全性好。
目的：探討拉西地平聯閤阿託伐他汀鈣治療高血壓閤併冠心病患者的臨床效果。方法選擇2014年1月～2015年2月于我院確診為高血壓閤併冠心病患者94例作為研究對象，根據治療藥物不同分為治療組（56例）和對照組（38例），對照組採用硝苯地平控釋片治療，治療組採用拉西地平聯閤阿託伐他汀鈣聯閤治療，比較兩組患者治療後的血壓、血脂水平的變化等臨床療效。結果與對照組比較治療組治療總有效率明顯較高，兩組差異有統計學意義（P＜0.05）。治療後兩組患者收縮壓、舒張壓、三酰甘油、總膽固醇水平等均明顯低于治療前，但治療後治療組各指標水平改善水平優于對照組，兩組差異有統計學意義（P＜0.05）。結論拉西地平與阿託伐他汀鈣聯閤用藥治療高血壓閤併冠心病能夠起到協同增效的作用，可以有效控製患者的血壓水平，併改善患者血脂情況，安全性好。
목적：탐토랍서지평연합아탁벌타정개치료고혈압합병관심병환자적림상효과。방법선택2014년1월～2015년2월우아원학진위고혈압합병관심병환자94례작위연구대상，근거치료약물불동분위치료조（56례）화대조조（38례），대조조채용초분지평공석편치료，치료조채용랍서지평연합아탁벌타정개연합치료，비교량조환자치료후적혈압、혈지수평적변화등림상료효。결과여대조조비교치료조치료총유효솔명현교고，량조차이유통계학의의（P＜0.05）。치료후량조환자수축압、서장압、삼선감유、총담고순수평등균명현저우치료전，단치료후치료조각지표수평개선수평우우대조조，량조차이유통계학의의（P＜0.05）。결론랍서지평여아탁벌타정개연합용약치료고혈압합병관심병능구기도협동증효적작용，가이유효공제환자적혈압수평，병개선환자혈지정황，안전성호。
ObjectiveTo investigate the clinical results of hypertension combined coronary heart disease treated with lacidipine and atorvastatin calcium. Methods94 cases with hypertension and coronary heart disease were selected from January 2014 to February 2015 in our hospital as research subjects,all the cases were divided into the treatment group(56 cases) and the control group(38 cases),the cases in control group used nifedipine GITS treatment,the cases in treatment group used lacidipine combination with atorvastatin calcium,and the clinical efficacy of the change of blood pressure and blood lipid levels of the two groups were compared.Results The total efficiency of the treatment group was significantly higher than the control group,the difference was statistically significant (P<0.05).After treatment,diastolic,systolic blood pressure,triglycerides, total cholesterol levels of two groups were significantly lower than before treatment,the degree of decline in the index level of the treatment group was better than the control group,the difference was statistically significant (P<0.05).Conclusion The combination therapy with lacidipine and atorvastatin calcium of hypertension and coronary heart disease can play a synergistic effect,can effectively control blood pressure levels in patients,improve lipid profile, with high security.
