CAJ | 학술논문

目的：探讨亚急性甲状腺炎合并 Graves 病的发病机制、临床表现、诊断、治疗及转归情况。方法回顾性分析2009年2月～2013年4月期间12例亚急性甲状腺炎合并 Graves 病患者的临床资料。结果所有患者亚急性甲状腺炎症状和体征均典型，83%患者检测结果示摄碘率和甲状腺受体抗体(TRAb)滴度均明显升高且红细胞沉降率明显增快。结论临床上对于有亚急性甲状腺炎症状伴摄碘率、TRAb 滴度显著升高及甲状腺毒性症状持续不缓解者，应考虑亚急性甲状腺炎合并 Graves 病。
목적：탐토아급성갑상선염합병 Graves 병적발병궤제、림상표현、진단、치료급전귀정황。방법회고성분석2009년2월～2013년4월기간12례아급성갑상선염합병 Graves 병환자적림상자료。결과소유환자아급성갑상선염증상화체정균전형，83%환자검측결과시섭전솔화갑상선수체항체(TRAb)적도균명현승고차홍세포침강솔명현증쾌。결론림상상대우유아급성갑상선염증상반섭전솔、TRAb 적도현저승고급갑상선독성증상지속불완해자，응고필아급성갑상선염합병 Graves 병。
Objective To discuss the pathogenesis, clinical manifestations, diagnosis, treatment of the subacute thyroiditis complicated with Graves disease. Methods Clinical data was retrospectively analyzed in 12 cases with subacute thyroiditis complicated by Graves disease from the February of 2009 to the April of 2013. Results All patients have evident signs and symptoms of subacute thyroiditis.83% of the patients showed an elevation of the uptakes of radioactive iodine and the erythrocyte sedimentation rate. The positive rate of the thyroid receptor antibody was 91%. Conclusion If patients with confirmed evidence of subacute thyroiditis were accompanied with markedly elevated titers of thyroid receptor antibody or high uptakes of radioactive iodine or persistent thyrotoxicosis, coexistence of both diseases should be suspected.