中华实验外科杂志
中華實驗外科雜誌
중화실험외과잡지
CHINESE JOURNAL OF EXPERIMENTAL SURGERY
2015年
8期
1936-1939
,共4页
刘增钦%杨江根%张忠%刘南新
劉增欽%楊江根%張忠%劉南新
류증흠%양강근%장충%류남신
输尿管支架管%膀胱输尿管返流
輸尿管支架管%膀胱輸尿管返流
수뇨관지가관%방광수뇨관반류
Ureteral stent%Vesicoureteral reflux
目的 制备两款具有抗返流设计的新型输尿管支架管并通过体外实验验证其有效性.方法 设计并制备两款新型抗返流输尿管支架管(Q-1型、Q-2型).将60根普通输尿管支架管随机分为3组(A、B、C组),每组各20根.A组改造成Q-1型抗返流输尿管支架管,B组改造成Q-2型抗返流输尿管支架管.通过体外实验检测3组输尿管支架管的引流通畅性与抗返流性能.并通过体外模拟输尿管支架管置管过程,测定并比较3组支架管在置管过程的阻力.结果 成功制作两款新型抗返流输尿管支架管(Q-1型和Q-2型).在体外实验中,A组和B组输尿管支架管中均有20根支架管具有抗返流性能(100％),而C组输尿管支架管0根支架管具有抗返流性能(0％).3组支架管在抗返流性能差异有统计学意义(P＜0.01).在3种不同压力下[30、20、12 cmH2O(1 cmH2O =0.098 kPa)]3组输尿管支架管引流速度分别为(23.25±1.80)、(15.92±1.42)、(10.11±1.23) ml/min,(25.18±2.16)、(18.15±1.58)、(12.46±2.01) ml/min,(51.38±1.78)、(39.31±2.23)、(27.09±1.46) ml/min,引流通畅性能差异有统计学意义(P＜0.01).3组支架管在体外模拟两种不同方式置管过程测得的阻力分别是(0.797±0.093)、(0.997±0.122)N,(0.746±0.043)、(0.786±0.076) N,(0.683±0.094)、(0.654±0.087) N(P＜0.05).结论 Q-1型和Q-2型抗返流输尿管支架管具备极佳的抗返流性能和足够良好的引流通畅性,在置管方面也易于操作.
目的 製備兩款具有抗返流設計的新型輸尿管支架管併通過體外實驗驗證其有效性.方法 設計併製備兩款新型抗返流輸尿管支架管(Q-1型、Q-2型).將60根普通輸尿管支架管隨機分為3組(A、B、C組),每組各20根.A組改造成Q-1型抗返流輸尿管支架管,B組改造成Q-2型抗返流輸尿管支架管.通過體外實驗檢測3組輸尿管支架管的引流通暢性與抗返流性能.併通過體外模擬輸尿管支架管置管過程,測定併比較3組支架管在置管過程的阻力.結果 成功製作兩款新型抗返流輸尿管支架管(Q-1型和Q-2型).在體外實驗中,A組和B組輸尿管支架管中均有20根支架管具有抗返流性能(100％),而C組輸尿管支架管0根支架管具有抗返流性能(0％).3組支架管在抗返流性能差異有統計學意義(P＜0.01).在3種不同壓力下[30、20、12 cmH2O(1 cmH2O =0.098 kPa)]3組輸尿管支架管引流速度分彆為(23.25±1.80)、(15.92±1.42)、(10.11±1.23) ml/min,(25.18±2.16)、(18.15±1.58)、(12.46±2.01) ml/min,(51.38±1.78)、(39.31±2.23)、(27.09±1.46) ml/min,引流通暢性能差異有統計學意義(P＜0.01).3組支架管在體外模擬兩種不同方式置管過程測得的阻力分彆是(0.797±0.093)、(0.997±0.122)N,(0.746±0.043)、(0.786±0.076) N,(0.683±0.094)、(0.654±0.087) N(P＜0.05).結論 Q-1型和Q-2型抗返流輸尿管支架管具備極佳的抗返流性能和足夠良好的引流通暢性,在置管方麵也易于操作.
목적 제비량관구유항반류설계적신형수뇨관지가관병통과체외실험험증기유효성.방법 설계병제비량관신형항반류수뇨관지가관(Q-1형、Q-2형).장60근보통수뇨관지가관수궤분위3조(A、B、C조),매조각20근.A조개조성Q-1형항반류수뇨관지가관,B조개조성Q-2형항반류수뇨관지가관.통과체외실험검측3조수뇨관지가관적인류통창성여항반류성능.병통과체외모의수뇨관지가관치관과정,측정병비교3조지가관재치관과정적조력.결과 성공제작량관신형항반류수뇨관지가관(Q-1형화Q-2형).재체외실험중,A조화B조수뇨관지가관중균유20근지가관구유항반류성능(100％),이C조수뇨관지가관0근지가관구유항반류성능(0％).3조지가관재항반류성능차이유통계학의의(P＜0.01).재3충불동압력하[30、20、12 cmH2O(1 cmH2O =0.098 kPa)]3조수뇨관지가관인류속도분별위(23.25±1.80)、(15.92±1.42)、(10.11±1.23) ml/min,(25.18±2.16)、(18.15±1.58)、(12.46±2.01) ml/min,(51.38±1.78)、(39.31±2.23)、(27.09±1.46) ml/min,인류통창성능차이유통계학의의(P＜0.01).3조지가관재체외모의량충불동방식치관과정측득적조력분별시(0.797±0.093)、(0.997±0.122)N,(0.746±0.043)、(0.786±0.076) N,(0.683±0.094)、(0.654±0.087) N(P＜0.05).결론 Q-1형화Q-2형항반류수뇨관지가관구비겁가적항반류성능화족구량호적인류통창성,재치관방면야역우조작.
Objective To develop two advanced double J stents with anti-reflux device and evaluate the effectiveness of these new double J stents by in vitro studies.Methods We manufactured two newly designed double J stents with anti-reflux device (Model Q-1,and Model Q-2).Sixty pieces of standard double J stents were randomly divided into three groups:A,B and C (n =20 each).Group A was given Model Q-1,and group B Model Q-2.In vitro testing was conducted to evaluate the drainage and antireflux characteristics of Model Q-1 (group A),Model Q-2 (group B) and standard double J stent (group C).In an in vitro experimental model,we compared the resistance of ureteral placement among the three groups and the force of stent insertion was measured.Results Two newly designed double J stents with anti-reflux device (Model Q-1,and Model Q-2) were manufactured.In the in vitro testing,there was significant difference among the three groups in anti-reflux properties (P ＜ 0.01).Twenty cases in both group A and group B had positive results of anti-reflux (100％,20/20),while 0 case in group C (0％,0/20).In terms of drainage properties,the flow rate [under different pressues of 30,20 and 12 cmH2O (1 cmH2O =0.098 kPa)] was (23.25 ± 1.80),(15.92 ± 1.42) and (10.11 ± 1.23) ml/min in group A,(25.18 ± 2.16),(18.15 ± 1.58) and (12.46 ± 2.01) ml/min in group B,and (51.38 ± 1.78),(39.31 ±2.23) and (27.09 ± 1.46) ml/min in group C,respectively.There were notable differences among three groups (P ＜0.01).The force of stent insertion in two different ways was (0.797±0.093) and (0.997 ±0.122) N in group A,(0.746 ±0.043) and (0.786 ±0.076) N in group B,and (0.683 ± 0.094) and (0.654 ± 0.087) N in group C (P ＜ 0.05).Conclusion The two newly designed double J stents with anti-reflux device (Model Q-1,and Model Q-2) had favorable drainage and perfect anti-reflux properties,and were easily placed over a guidwire.
