CAJ | 학술논문

背景:国外最新的研究成果显示,与传统髓芯减压治疗比较,多孔钛合金支撑棒置入治疗距骨骨折的疗效有明显提升,同时降低了手术难度.目的:对比多孔钛合金支撑棒与髓芯减压治疗早期距骨骨坏死的临床效果.方法:纳入早期距骨骨坏死患者60例,其中男33例,女27例,年龄18-73岁,采取随机数表法均分为试验组与对照组,试验组进行多孔钛合金支撑棒置入治疗,对照组进行传统的髓芯减压治疗.对比两组治疗后12个月的坏死范围进展情况,治疗后24周内的感染率及踝关节肿胀情况,以及治疗12个月内的跛行发生率.结果与结论:治疗后12个月,试验组骨坏死进展情况明显低于对照组(P < 0.05).试验组治疗后即刻、治疗后2周、治疗后4周、治疗后12周、治疗后24周的感染率及踝关节肿胀率均低于对照组(P < 0.05),治疗后1,3,6,12个月的跛行发生率明显低于对照组(P < 0.05).试验组未发生与植入材料相关的不良反应.表明以多孔钛合金支撑棒置入治疗早期距骨骨坏死有利于骨组织的再生,促进踝关节功能恢复.
배경:국외최신적연구성과현시,여전통수심감압치료비교,다공태합금지탱봉치입치료거골골절적료효유명현제승,동시강저료수술난도.목적:대비다공태합금지탱봉여수심감압치료조기거골골배사적림상효과.방법:납입조기거골골배사환자60례,기중남33례,녀27례,년령18-73세,채취수궤수표법균분위시험조여대조조,시험조진행다공태합금지탱봉치입치료,대조조진행전통적수심감압치료.대비량조치료후12개월적배사범위진전정황,치료후24주내적감염솔급과관절종창정황,이급치료12개월내적파행발생솔.결과여결론:치료후12개월,시험조골배사진전정황명현저우대조조(P < 0.05).시험조치료후즉각、치료후2주、치료후4주、치료후12주、치료후24주적감염솔급과관절종창솔균저우대조조(P < 0.05),치료후1,3,6,12개월적파행발생솔명현저우대조조(P < 0.05).시험조미발생여식입재료상관적불량반응.표명이다공태합금지탱봉치입치료조기거골골배사유리우골조직적재생,촉진과관절공능회복.
BACKGROUND:Latest researches outside China have shown that compared with conventional core decompression therapy, porous titanium aloy rod implantation for the treatment of talus fracture has better therapeutic effects and more greatly reduces the difficulties of operation. OBJECTIVE: To compare the clinical effects of porous titanium aloy rod implantation and core decompression therapy for the treatment of early-stage osteonecrosis of the talus. METHODS:Sixty patients with early-stage osteonecrosis of the talus, 33 males and 27 females, aged from 18 to 73 years, were included in the experiment. The patients were randomly and evenly divided into experimental group and control group. The patients in the experimental group received porous titanium aloy rod implantation, while the patients in the control group were subjected to conventional core decompression therapy. The progression of necrotic area after 12 months of treatment, infection rate and ankle sweling within 24 weeks after treatment and lameness incidence within 12 months of treatment were compared between the experimental and control groups. RESULTS AND CONCLUSION: At 12 months after treatment, the progression of osteonecrosis of the talus in the experimental group was significantly slower than that in the control group (P < 0.05). The infection rate and ankle sweling rate immediately and 2, 4, 12 and 24 weeks after treatment in the experimental group were significantly lower than those in the control group (P < 0.05). At 1, 3, 6 and 12 months after treatment, the lameness incidence of patients in the experimental group was significantly lower than that in the control group (P < 0.05). There were no adverse reactions associated with the implant materials in the experimental group. These results demonstrate that porous titanium aloy rod implantation contributes to bone tissue regeneration and promotes ankle function restoration in patients with early-stage osteonecrosis of the talus.