CAJ | 학술논문

目的：观察在联合用药和给药剂量两个因素干预后，药物不良反应发生率的变化情况，以便于确定有效的干预措施，指导临床合理用药，确保中药注射剂使用的安全有效。方法选取我院收治的558例患者，随机分为干预组和非干预组，每组229例患者，通过制定用药标准，宣传教育，监督检查进行干预，记录两组患者不良反应发生率。结果在中药注射剂的临床使用过程中，干预组在通过联合用药和给药剂量干预后，与非干预组相比较不良反应发生率降低，差异比较具有统计学意义（P ＜0.01）。结论采用有效的干预措施能够降低不良反应的发生率，使得中药注射剂在临床应用中更加安全合理。
목적：관찰재연합용약화급약제량량개인소간예후，약물불량반응발생솔적변화정황，이편우학정유효적간예조시，지도림상합리용약，학보중약주사제사용적안전유효。방법선취아원수치적558례환자，수궤분위간예조화비간예조，매조229례환자，통과제정용약표준，선전교육，감독검사진행간예，기록량조환자불량반응발생솔。결과재중약주사제적림상사용과정중，간예조재통과연합용약화급약제량간예후，여비간예조상비교불량반응발생솔강저，차이비교구유통계학의의（P ＜0.01）。결론채용유효적간예조시능구강저불량반응적발생솔，사득중약주사제재림상응용중경가안전합리。
Objective To observe the in combination and dosage of two factors to intervention, adverse drug reactions occur rate changes, and record the incidence of adverse reactions of the two groups of patients. Methods 558 cases in our hospital were selected and randomly divided into intervention group and the non-intervention group, 229 cases in each group, through the development of drug standards, education, supervision and inspection of intervention, the two groups were recorded incidence of adverse reactions.Results In the course of the clinical use of traditional Chinese medicine injection rate, the intervention group by combined medication and dosage of intervention and non intervention group phase and compared the adverse reactions occurrence rate is reduced. The difference had statistical significance (P<0.01). Conclusion The effective intervention measures can reduce the incidence of adverse reactions, making TCMI in clinical application is more reasonable and safe.