CAJ | 학술논문

目的：探讨2型糖尿病患者维生素 D 缺乏与糖脂代谢的相关性。方法：选取2型糖尿病患者200例，根据血25（OH）D3浓度分为维生素 D缺乏组（＜10ng／ml）和维生素 D 非缺乏组（≥10ng／ml）。观察两组间糖脂代谢指标（空腹血糖、空腹 C 肽、餐后2小时血糖、餐后2小时 C 肽、糖化血红蛋白、总胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白）的差异。结果：维生素 D 缺乏组糖化血红蛋白水平高于维生素 D 非缺乏组（P ＜0．05）。空腹及餐后2小时血糖及 C 肽、总胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白两组间无明显统计学差异。结论：在2型糖尿病患者中，长期血糖控制不佳可能与维生素 D 缺乏有关。
목적：탐토2형당뇨병환자유생소 D 결핍여당지대사적상관성。방법：선취2형당뇨병환자200례，근거혈25（OH）D3농도분위유생소 D결핍조（＜10ng／ml）화유생소 D 비결핍조（≥10ng／ml）。관찰량조간당지대사지표（공복혈당、공복 C 태、찬후2소시혈당、찬후2소시 C 태、당화혈홍단백、총담고순、감유삼지、고밀도지단백、저밀도지단백）적차이。결과：유생소 D 결핍조당화혈홍단백수평고우유생소 D 비결핍조（P ＜0．05）。공복급찬후2소시혈당급 C 태、총담고순、감유삼지、고밀도지단백、저밀도지단백량조간무명현통계학차이。결론：재2형당뇨병환자중，장기혈당공제불가가능여유생소 D 결핍유관。
Objective:To evaluate the association between vitamin D deficiency and glucolipid metabolism in patients with type 2 diabetes.Methods:200 patients with type 2 diabetes were included,which were divided into two groups based on serum 25(OH)D3 levels:vitamin D deficiency group [25(OH)D3 <1 0ng/ml]and vitamin D non -deficiency group [25(OH)D3 ≥1 0ng/ml].The difference of the two group in glucolipid metabolism parameters (fasting blood glucose(FBG),fasting C peptide (FCP),2 hours blood glucose,2 hours C peptide,glycosylated hemoglobin,total cholesterol,triglyceride,high density lipo-protein,low density lipoprotein)were analyzed.Results:The glycosylated hemoglobin level in the vitamin D deficiency group was higher than the non -defi-ciency group (P <0.05),but there were no obvious statistical difference in the other parameters between the two group.Conclusion:The blood glucose poorly controlled undertaking may be related to the vitamin D deficiency in the patients with type 2 diabetes.