CAJ | 학술논문

目的探讨胶东地区尿路结石的成分组成及临床意义.方法采取胶东地区尿路结石标本1 643例.其中男1 045例,女598例,年龄4个月～ 82岁.男性平均年龄(38.54±17.60)岁,女性平均年龄(43.22±15.30)岁.肾结石1 056例(64.34％),输尿管结石576例(35.05％),膀胱结石11例(0.60％).所有结石均采用LIIR型结石红外光谱自动分析系统分析.解析结果均行红外光谱人工解析验证.结果结石总体构成比上,一水草酸钙为主要成分的结石854例(51.98％),碳酸磷灰石为主要成分的结石197例(11.50％),无水尿酸为主要成分的结石461例(28.06％),二水草酸钙结石28例(1.71％),六水磷酸铵镁结石93例(5.66％),胱氨酸结石8例(0.31％),尿酸铵结石4例(0.25％).结石的组合成分上,混合性结石1 014例(61.72％),单一成分结石629例(38.28％).结论胶东地区尿酸结石相对较多,结石红外光谱自动分析系统分析尿路结石成分具有准确、自动、快捷等优点.
목적 탐토효동지구뇨로결석적성분조성급림상의의.방법 채취효동지구뇨로결석표본1 643례.기중남1 045례,녀598례,년령4개월～ 82세.남성평균년령(38.54±17.60)세,녀성평균년령(43.22±15.30)세.신결석1 056례(64.34％),수뇨관결석576례(35.05％),방광결석11례(0.60％).소유결석균채용LIIR형결석홍외광보자동분석계통분석.해석결과균행홍외광보인공해석험증.결과 결석총체구성비상,일수초산개위주요성분적결석854례(51.98％),탄산린회석위주요성분적결석197례(11.50％),무수뇨산위주요성분적결석461례(28.06％),이수초산개결석28례(1.71％),륙수린산안미결석93례(5.66％),광안산결석8례(0.31％),뇨산안결석4례(0.25％).결석적조합성분상,혼합성결석1 014례(61.72％),단일성분결석629례(38.28％).결론 효동지구뇨산결석상대교다,결석홍외광보자동분석계통분석뇨로결석성분구유준학、자동、쾌첩등우점.
Objective To determine the composition of urinary stones in eastern Shandong region using LIIR Automatic Analysis System of Infrared Spectroscopy and discuss its clinical value.Methods Urinary stone samples were collected from 1 643 patients in eastern Shandong area.Patients aged between 4 months and 82 years old,including 1 045 males [average age of (38.54 ± 17.60) years old] and 598 females [average age of (43.22 ± 15.30) years old].The stone was located in the kidney in 1 056 cases (60.34％),ureter in 576 cases (35.05％) and bladder in 11 cases (0.60％).Compositions of stones were analyzed by LIIR Automatic Analysis System of Infrared Spectroscopy.The results were verified by manual analysis of the spectrogram accompanied by polarizing microscopy and chemical analysis when necessary.Results Regarding the compositions of stones,the main component of stones was calcium oxalate monohydrate in 854 cases (51.98％),anhydrous uric acid in 461 cases (28.06％),carbonate apatite in 197 cases (11.50％),ammonium magnesium phosphate hexahydrate in 93 cases (5.66％),calcium oxalate dehydrate in 28 cases (1.71％),cysteine in 8 cases (0.31％) and ammonium urate in 4 cases (0.25％).Regarding the constitution of stones,there were 1 014 cases (61.72％) of mixedstones,and 629 cases (38.28％) of stones with a single component.Conclusion In eastern Shandong region uric acid stone was the most common type of urinary stones.The Automatic Analysis System of Infrared Spectroscopy has many advantages in accuracy,automation and speediness in analyzing the composition of urinary stones and is worthy of routine clinical application.