CAJ | 학술논문

目的：初步探讨相位校正多回波GRE Dixon序列在原发性肝癌诊断中的作用。材料与方法利用GRE Dixon序列扫描22例原发性肝癌患者，分析其在GRE Dixon序列生成的水像、脂像、水/脂相位图、R2*像的影像特点，并与传统T1、T2像及病理结果对照。结果胆管细胞癌与含脂肝细胞癌在水像上大多呈低信号，不含脂的肝细胞癌在水像上大多呈等信号。多数肿瘤中的出血、坏死在R2*像能够显示，优于T2像。胆管细胞癌的R2*值低于肝细胞癌(P=0.003)。R2*像中肿瘤与肝组织的对比噪声比低于T2像。结论分析相位校正多回波GRE Dixon的图像能够判断肝脏肿瘤组织内的出血、坏死、脂变、纤维成份，有利于胆管细胞癌与肝细胞癌的鉴别。
목적：초보탐토상위교정다회파GRE Dixon서렬재원발성간암진단중적작용。재료여방법이용GRE Dixon서렬소묘22례원발성간암환자，분석기재GRE Dixon서렬생성적수상、지상、수/지상위도、R2*상적영상특점，병여전통T1、T2상급병리결과대조。결과담관세포암여함지간세포암재수상상대다정저신호，불함지적간세포암재수상상대다정등신호。다수종류중적출혈、배사재R2*상능구현시，우우T2상。담관세포암적R2*치저우간세포암(P=0.003)。R2*상중종류여간조직적대비조성비저우T2상。결론분석상위교정다회파GRE Dixon적도상능구판단간장종류조직내적출혈、배사、지변、섬유성빈，유리우담관세포암여간세포암적감별。
AbstractObjective:To clarify the significance of multi-echo GRE Dixon in the diagnosis of primary hepatocarcinoma.Materials and Methods:Twenty-two patients with hepatocarcinoma proved pathologically by surgery and biopsy underwent liver MRI scanning with a phase correction multi-echo GRE Dixon sequence. We analyze their imaging features of tumor in water only imaging, fat only imaging, water/fat phase mapping, R2* mapping and make a contrast with imaging of in-phase and opposed-phase, T2 weighted imaging and histopathological results.Results:Intrahepatic cholangiocarcinoma and hepatocellular carcinoma with fatty degeneration usually shows hypointensity on water only imaging and hepatocellular carcinoma without fatty degeneration shows isointensity on water only image. Most of the tumors can be seen more necrosis and hemorrhage on R2* mapping than T2 weighted imaging. The value of R2* of Intrahepatic cholangiocarcinoma is lower than that of Hepatocellular carcinoma and theP value is 0.003. R2* mapping has a lower contrast to noise ratio of tumor and hepatic tissue than T2 weighted imaging.Conclusion:We can distinguish necrosis, hemorrhage, fatty degeneration and fibre in the liver tumor by phase correction multi-echo GRE Dixon, which plays an important role in the differential diagnosis of intrahepatic cholangiocarcinoma and hepatocarcinoma.