磁共振成像
磁共振成像
자공진성상
CHINESE JOURNAL OF MAGNETIC RESONANCE IMAGING
2015年
8期
599-602
,共4页
肾肿瘤%磁共振成像%动态增强%平滑肌瘤%脂肪瘤
腎腫瘤%磁共振成像%動態增彊%平滑肌瘤%脂肪瘤
신종류%자공진성상%동태증강%평활기류%지방류
Kidney neoplasms%Magnetic resonance imaging%Dynamic enhancement%Leiomyoma%Lipoma
目的:探讨定量动态增强磁共振成像(dynamic contrast-enhanced MRI, DCE-MRI)对肾透明细胞癌、乏脂肪肾血管平滑肌脂肪瘤的鉴别能力。材料与方法收集38例经手术病理证实的肾脏肿瘤患者,其中肾透明细胞癌26例,乏脂肪肾血管平滑肌脂肪瘤12例,术前均行常规MRI、DCE-MRI扫描,选取感兴趣区测量肿瘤的动态增强定量参数Ktrans(容量转移常数)、Kep(速率常数)、Ve(血管外细胞外间隙容积比),并对得到的数据进行分析。结果经DCE-MRI检查的26例肾透明细胞癌患者中病灶区在动态增强扫描的早期强化,定量参数Ktrans、Kep、Ve均值分别为(0.625±0.313) min-1、(1.764±1.105) min-1、(-0.341±0.207);12例乏脂肪肾血管平滑肌脂肪瘤的定量参数K trans、K ep、Ve均值分别为(0.061±0.023) min-1、(0.916±0.313) min-1、(-0.146±0.074)。Ktrans在肾透明细胞癌与乏脂肪肾血管平滑肌脂肪瘤间的差异有统计学意义(t=4.063,P<0.05), Kep、Ve在肾透明细胞癌与乏脂肪肾血管平滑肌脂肪瘤间的差异无统计学意义(t值分别为2.153、0.5,P>0.05)。结论定量DCE-MRI技术对肾透明细胞癌与乏脂肪肾血管平滑肌脂肪瘤有良好的鉴别诊断作用。
目的:探討定量動態增彊磁共振成像(dynamic contrast-enhanced MRI, DCE-MRI)對腎透明細胞癌、乏脂肪腎血管平滑肌脂肪瘤的鑒彆能力。材料與方法收集38例經手術病理證實的腎髒腫瘤患者,其中腎透明細胞癌26例,乏脂肪腎血管平滑肌脂肪瘤12例,術前均行常規MRI、DCE-MRI掃描,選取感興趣區測量腫瘤的動態增彊定量參數Ktrans(容量轉移常數)、Kep(速率常數)、Ve(血管外細胞外間隙容積比),併對得到的數據進行分析。結果經DCE-MRI檢查的26例腎透明細胞癌患者中病竈區在動態增彊掃描的早期彊化,定量參數Ktrans、Kep、Ve均值分彆為(0.625±0.313) min-1、(1.764±1.105) min-1、(-0.341±0.207);12例乏脂肪腎血管平滑肌脂肪瘤的定量參數K trans、K ep、Ve均值分彆為(0.061±0.023) min-1、(0.916±0.313) min-1、(-0.146±0.074)。Ktrans在腎透明細胞癌與乏脂肪腎血管平滑肌脂肪瘤間的差異有統計學意義(t=4.063,P<0.05), Kep、Ve在腎透明細胞癌與乏脂肪腎血管平滑肌脂肪瘤間的差異無統計學意義(t值分彆為2.153、0.5,P>0.05)。結論定量DCE-MRI技術對腎透明細胞癌與乏脂肪腎血管平滑肌脂肪瘤有良好的鑒彆診斷作用。
목적:탐토정량동태증강자공진성상(dynamic contrast-enhanced MRI, DCE-MRI)대신투명세포암、핍지방신혈관평활기지방류적감별능력。재료여방법수집38례경수술병리증실적신장종류환자,기중신투명세포암26례,핍지방신혈관평활기지방류12례,술전균행상규MRI、DCE-MRI소묘,선취감흥취구측량종류적동태증강정량삼수Ktrans(용량전이상수)、Kep(속솔상수)、Ve(혈관외세포외간극용적비),병대득도적수거진행분석。결과경DCE-MRI검사적26례신투명세포암환자중병조구재동태증강소묘적조기강화,정량삼수Ktrans、Kep、Ve균치분별위(0.625±0.313) min-1、(1.764±1.105) min-1、(-0.341±0.207);12례핍지방신혈관평활기지방류적정량삼수K trans、K ep、Ve균치분별위(0.061±0.023) min-1、(0.916±0.313) min-1、(-0.146±0.074)。Ktrans재신투명세포암여핍지방신혈관평활기지방류간적차이유통계학의의(t=4.063,P<0.05), Kep、Ve재신투명세포암여핍지방신혈관평활기지방류간적차이무통계학의의(t치분별위2.153、0.5,P>0.05)。결론정량DCE-MRI기술대신투명세포암여핍지방신혈관평활기지방류유량호적감별진단작용。
AbstractObjective:To explore the differential diagnosis value of quantitative dynamic contrast-enhanced MRI(DCE-MRI) of renal clear cell carcinoma and renal angiomyolipomas with minimal fat. Materials and Methods:Twenty-six cases with renal clear cell carcinoma, twelve cases with renal angiomyolipomas with minimal fat confirmed by operation, underwent the examination of MRI conventional scanning, and DCE-MRI. ROI were drawn to record the quantitative parameters average values of Ktrans, Kep, Ve. Results were statistically treated with SPSS 13.0.Results:Twenty-six cases with renal clear cell carcinoma showed obvious enhancement in the early phase of DCE-MRI. The Ktrans, Kep, Ve average value of renal cell carcinoma was (0.625±0.313) min-1, (1.764±1.105) min-1, (-0.341±0.207), and the Ktrans, Kep, Ve average value of renal angiomyolipomas with minimal fat was (0.061±0.023) min-1, (0.916±0.313) min-1, (-0.146±0.074). Ktrans value was statistically significant in the differences between renal cell carcinoma and renal angiomyolipomas with minimal fat. t value 4.063,P<0.05. Kep, Ve value were not statistically signiifcant in the differences between renal cell carcinoma and renal angiomyolipomas with minimal fat,t value 2.153, 0.5,P>0.05.Conclusion:Quantitative DCE-MRI could differentiate renal clear cell carcinoma from renal angiomyolipomas with minimal fat.