CAJ | 학술논문

目的：探讨慢性肾衰竭（CRF）维持性血液透析（MHD）患者的认知功能变化，为临床护理工作提供理论依据。方法采用中文版蒙特利尔认知评估量表、听觉词语回忆测验、连线测验、Stroop色词测验、数字广度测验、符号数字转换测验以及言语流畅性测验对69例MHD患者及40例健康对照组进行认知评定。结果 MHD组认知功能障碍的发生率高于对照组（P＜0.05）。在记忆测验方面，MHD组患者听觉词语回忆测验及复杂图片测验得分均低于对照组（P＜0.05）；非记忆测验方面，MHD组言语流畅性测验得分低于对照组（P＜0.05），连线测验-A和连线测验-B耗时数比对照组延长（P＜0.05）；Stroop色词测验B、C及复杂图片测验得分均低于对照组（P＜0.05）。结论MHD患者存在多方面的认知功能损害，主要表现在记忆力减退、注意力和知觉运动速度下降、执行功能和语言能力降低，应及早采取护理干预措施。
목적：탐토만성신쇠갈（CRF）유지성혈액투석（MHD）환자적인지공능변화，위림상호리공작제공이론의거。방법채용중문판몽특리이인지평고량표、은각사어회억측험、련선측험、Stroop색사측험、수자엄도측험、부호수자전환측험이급언어류창성측험대69례MHD환자급40례건강대조조진행인지평정。결과 MHD조인지공능장애적발생솔고우대조조（P＜0.05）。재기억측험방면，MHD조환자은각사어회억측험급복잡도편측험득분균저우대조조（P＜0.05）；비기억측험방면，MHD조언어류창성측험득분저우대조조（P＜0.05），련선측험-A화련선측험-B모시수비대조조연장（P＜0.05）；Stroop색사측험B、C급복잡도편측험득분균저우대조조（P＜0.05）。결론MHD환자존재다방면적인지공능손해，주요표현재기억력감퇴、주의력화지각운동속도하강、집행공능화어언능력강저，응급조채취호리간예조시。
Objective To explore the changes of cognitive function in patients with chronic renal failure and receiving maintenance hemodialysis therapy.Methods A convenience sample of 69 MHD patients and 40 healthy people with normal kidney function matched for demographic information, vascular disease and other comorbidity were included. A battery of eight validated neuropsychological tests was administered to estimate their cognitive function, including: MoCA, Auditory Verbal Memory Test(AVMT), Symbol digit modalities test(SDMT), Digit span test (DST), Rey-Osterrieth Complex Figure Test(CFT) ,Trail Making Test (TMT), Stroop Color Words Test(SCWT), Verbal Fluency Test(VFT). Results Compare to controls, the percentage of subjects with impairment was significantly higher in MHD subjects. In each tested cognitive domain, including memory and non-memory domain, MHD subjects had signiifcantly lower scores.Conclusion MHD patients had various cognitive impairment and performed signiifcantly worse on the domain of memory, attention and processing, executive function, language. Early initiation of proper treatment may help lower the incidence of cognitive impairment.