甘肃医药
甘肅醫藥
감숙의약
Gansu Medical Journal
2015年
8期
561-563
,共3页
PiCCO%ARDS合并感染性休克%EGDT
PiCCO%ARDS閤併感染性休剋%EGDT
PiCCO%ARDS합병감염성휴극%EGDT
PiCCO%ARDS and septic shock%EGDT
目的:探讨脉波指示剂连续心排血量(PiCCO)指导下液体复苏在治疗ARDS合并感染性休克老年患者EGDT中的意义,为临床治疗提供指导依据。方法:选用自2013年5月来我院就诊ARDS合并感染性休克老年患者137例作为研究对象,随机分为对照组和治疗组,对照组30例(44.1%),按照常规进行EGDT治疗;治疗组38例(55.9%),采用PiCCO指导下EGDT治疗。记录两组患者在6h、12h、24h液体复苏情况,分析两组复苏1d后MAP、CVP、ScvO2、PaO2/FiO2和血管活性物质状况。并分析6h、12h、24h患者身体状况达标率以及4周后死亡率。结果:治疗组和对照组液体复苏在6h、12h、24h存在显著的统计学差异(t=3.102、3.296、2.853,P<0.05),1d血管活性药物用量治疗组显著低于对照组(t=1.895、4.216,P<0.05),在MAP、CVP、ScvO2、PaO2/FiO2上,治疗组要显著高于对照组(P<0.05)。两组之间24h达标率和4周后死亡率存在统计学差异(χ2=11.250、7.071,P<0.05)。结论:PiCCO指导下液体复苏对ARDS合并感染性休克老年患者EGDT临床具有良好的疗效,临床值得推广。
目的:探討脈波指示劑連續心排血量(PiCCO)指導下液體複囌在治療ARDS閤併感染性休剋老年患者EGDT中的意義,為臨床治療提供指導依據。方法:選用自2013年5月來我院就診ARDS閤併感染性休剋老年患者137例作為研究對象,隨機分為對照組和治療組,對照組30例(44.1%),按照常規進行EGDT治療;治療組38例(55.9%),採用PiCCO指導下EGDT治療。記錄兩組患者在6h、12h、24h液體複囌情況,分析兩組複囌1d後MAP、CVP、ScvO2、PaO2/FiO2和血管活性物質狀況。併分析6h、12h、24h患者身體狀況達標率以及4週後死亡率。結果:治療組和對照組液體複囌在6h、12h、24h存在顯著的統計學差異(t=3.102、3.296、2.853,P<0.05),1d血管活性藥物用量治療組顯著低于對照組(t=1.895、4.216,P<0.05),在MAP、CVP、ScvO2、PaO2/FiO2上,治療組要顯著高于對照組(P<0.05)。兩組之間24h達標率和4週後死亡率存在統計學差異(χ2=11.250、7.071,P<0.05)。結論:PiCCO指導下液體複囌對ARDS閤併感染性休剋老年患者EGDT臨床具有良好的療效,臨床值得推廣。
목적:탐토맥파지시제련속심배혈량(PiCCO)지도하액체복소재치료ARDS합병감염성휴극노년환자EGDT중적의의,위림상치료제공지도의거。방법:선용자2013년5월래아원취진ARDS합병감염성휴극노년환자137례작위연구대상,수궤분위대조조화치료조,대조조30례(44.1%),안조상규진행EGDT치료;치료조38례(55.9%),채용PiCCO지도하EGDT치료。기록량조환자재6h、12h、24h액체복소정황,분석량조복소1d후MAP、CVP、ScvO2、PaO2/FiO2화혈관활성물질상황。병분석6h、12h、24h환자신체상황체표솔이급4주후사망솔。결과:치료조화대조조액체복소재6h、12h、24h존재현저적통계학차이(t=3.102、3.296、2.853,P<0.05),1d혈관활성약물용량치료조현저저우대조조(t=1.895、4.216,P<0.05),재MAP、CVP、ScvO2、PaO2/FiO2상,치료조요현저고우대조조(P<0.05)。량조지간24h체표솔화4주후사망솔존재통계학차이(χ2=11.250、7.071,P<0.05)。결론:PiCCO지도하액체복소대ARDS합병감염성휴극노년환자EGDT림상구유량호적료효,림상치득추엄。
Objective: To s tudy the role of the monitoring technology of PiCCO in early goal-directed therapy (EGDT) on the old patients with ARDS and septic shock. Methods:68 patients with ARDS and septic shock admitted since May 2013 were randomized into 2 groups, 38 cases in the treatment group with PiCCO monitoring indicators for guiding fluid resuscitation and 30 cases in the control group with conventional fluid resuscitation indicators. Then we recorded the results on three time points, 6h, 12h, 24h in these two groups in which MAP, CVP, ScvO2, PaO2/FiO2 and the dosage of the vasoactive substances after 24h were analyzed. At last, we analyze patients’ health standard rate in 6h, 12h, 24h, and the death rate after 4 weeks. Results:The fluid resuscitation showed significant differences in these two groups in 6h、12h、24h(t=3.102, 3.296, 2.853, P<0.05). In the treatment group, the dosage of the vasoactive substances after 24h was significantly lower than that of the control group(t=1.895,4.216,P<0.05), the MAP, CVP, ScvO2, PaO2/FiO2 were significantly higher in the treatment group(P<0.05). There was a significant difference in 24h patient’s health standard rate and the death rate after 4 weeks (χ2=11.250,7.071,P<0.05). Conclusion: Application of PiCCO monitoring technology on EGDT in guidance of fluid resuscitation in the old patients with ARDS and septic shock is of great importance, which is worth of promoting.