中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2015年
13期
162-164
,共3页
超声造影%冠心病%颈动脉粥样硬化%新生微血管
超聲造影%冠心病%頸動脈粥樣硬化%新生微血管
초성조영%관심병%경동맥죽양경화%신생미혈관
Contrast-enhanced ultrasound%Coronary heart disease%Carotid atherosclerosis%Neovascularization
目的：评价超声造影对冠心病颈动脉粥样硬化斑块新生微血管的临床价值。方法选取我院心内科诊断为冠心病的住院患者，收集时间为2012年6月～2014年6月，作为冠心病组，共60例，随机选取来我院进行健康体检的人群60例，定义为对照组。记录患者血常规、尿常规、大便常规、生化指标如空腹血糖、总胆固醇、血甘油三酯、血低密度脂蛋白胆固醇等。常规B超下检查斑块数量，性质（软斑、硬斑），随后再记录造影剂使用后斑块的增强情况。结果冠心病组的软斑数量明显多于健康组，分别为（74块、5块），差异有统计学意义（P＜0.05），冠心病组硬斑与健康组相近分别为（38块、33块），差异无统计学意义（P＞0.05），本次研究发现通过B超造影下软斑明显增强，增强数量分别为（58块、3块），差异有统计学意义（P＜0.05），而硬斑增强不明显，增强数量分别为（4块、5块），差异无统计学意义（P＞0.05）。结论冠心病组软斑数量明显多于健康组，硬斑数量少于健康组，软斑内新生微血管明显多于硬斑，新生微血管数量、密度的增高是冠心病的危险因素。
目的：評價超聲造影對冠心病頸動脈粥樣硬化斑塊新生微血管的臨床價值。方法選取我院心內科診斷為冠心病的住院患者，收集時間為2012年6月～2014年6月，作為冠心病組，共60例，隨機選取來我院進行健康體檢的人群60例，定義為對照組。記錄患者血常規、尿常規、大便常規、生化指標如空腹血糖、總膽固醇、血甘油三酯、血低密度脂蛋白膽固醇等。常規B超下檢查斑塊數量，性質（軟斑、硬斑），隨後再記錄造影劑使用後斑塊的增彊情況。結果冠心病組的軟斑數量明顯多于健康組，分彆為（74塊、5塊），差異有統計學意義（P＜0.05），冠心病組硬斑與健康組相近分彆為（38塊、33塊），差異無統計學意義（P＞0.05），本次研究髮現通過B超造影下軟斑明顯增彊，增彊數量分彆為（58塊、3塊），差異有統計學意義（P＜0.05），而硬斑增彊不明顯，增彊數量分彆為（4塊、5塊），差異無統計學意義（P＞0.05）。結論冠心病組軟斑數量明顯多于健康組，硬斑數量少于健康組，軟斑內新生微血管明顯多于硬斑，新生微血管數量、密度的增高是冠心病的危險因素。
목적：평개초성조영대관심병경동맥죽양경화반괴신생미혈관적림상개치。방법선취아원심내과진단위관심병적주원환자，수집시간위2012년6월～2014년6월，작위관심병조，공60례，수궤선취래아원진행건강체검적인군60례，정의위대조조。기록환자혈상규、뇨상규、대편상규、생화지표여공복혈당、총담고순、혈감유삼지、혈저밀도지단백담고순등。상규B초하검사반괴수량，성질（연반、경반），수후재기록조영제사용후반괴적증강정황。결과관심병조적연반수량명현다우건강조，분별위（74괴、5괴），차이유통계학의의（P＜0.05），관심병조경반여건강조상근분별위（38괴、33괴），차이무통계학의의（P＞0.05），본차연구발현통과B초조영하연반명현증강，증강수량분별위（58괴、3괴），차이유통계학의의（P＜0.05），이경반증강불명현，증강수량분별위（4괴、5괴），차이무통계학의의（P＞0.05）。결론관심병조연반수량명현다우건강조，경반수량소우건강조，연반내신생미혈관명현다우경반，신생미혈관수량、밀도적증고시관심병적위험인소。
ObjectiveTo evaluate the clinical value of contrast-enhanced ultrasound in diagnosis of carotid atherosclerosis plaque neovascularization of patients with coronary heart disease.Methods 60 hospitalized patients who were diagnosed with coronary heart disease in the department of cardiovascular internal medicine of our hospital from June 2012 to June 2014 were selected as coronary heart disease group and 60 people who had physical examination in our hospital were randomly selected as control group. Blood routine, urine routine, stool routine, biochemical indexes including fasting blood glucose,total cholesterol,serum triglyceride,low-density lipoprotein cholesterol etc.of patients were recorded.The number of plaque and characters of plaque(soft plaque, hard plaque) were examined by routine B-ultrasound examination and then enhanced situation of plaque after using contrast agent was recorded.ResultsThe number of soft plaque 74 in the coronary heart disease group was significantly larger than that 5 in the control group,and the difference was statistically significant(P<0.05).The number of hard plaque in the coronary heart disease group was close to that in the control group, which was 38 and 33 respectively.The difference was not statistically significant(P>0.05).It was found in research that soft plaque was significantly enhanced and the increasing number was 58 and 3 respectively.The difference was statistically significant(P<0.05).While the enhancement of hard plaque was not significant and the increasing number was 4 and 5 respectively.The difference was not statistically significant(P>0.05).ConclusionThe number of soft plaque in the coronary heart disease group is significantly smaller than that in the control group while the number of hard plaque is larger than that in the control group.The number of neovascularization in soft plaque is significantly larger than that in hard plaque.The increasing number and density of neovascularization are risk factors to coronary heart disease.
