大家健康(中旬版)
大傢健康(中旬版)
대가건강(중순판)
GOOD HEALTH FOR ALL
2015年
8期
16-18
,共3页
张英%杜学文%陈世清%陆吉
張英%杜學文%陳世清%陸吉
장영%두학문%진세청%륙길
糖尿病%维生素 D 缺乏%下肢动脉疾病
糖尿病%維生素 D 缺乏%下肢動脈疾病
당뇨병%유생소 D 결핍%하지동맥질병
key word Diabetes mellitus%Vitamin D deficiency%Lower extremity arterial disease
目的:探讨2型糖尿病患者维生素 D 缺乏与下肢动脉疾病的相关性。方法:选取2型糖尿病患者206例,根据血25(OH)D3浓度分为维生素 D 缺乏组(<10ng/ml)和维生素 D 非缺乏组(≥10ng/ml)。采集临床资料数据,测定下肢动脉疾病指标踝肱比(ABI)。对血25(OH)D3水平及ABI 的关系进行方差分析及二项分类 logistic 回归分析。结果:在全部(206例)2型糖尿病患者中,维生素 D 缺乏组为84例(40.8%),维生素 D 非缺乏组122例(59.2%)。在维生素 D 缺乏组与非缺乏组中,已知的下肢动脉疾病危险因素(如年龄、BMI、腰围、高血压、吸烟、总胆固醇)无显著差异。维生素 D 缺乏组 ABI≤0.9的24例(28.6%),维生素 D 非缺乏组 ABI≤0.9的32例(26.2%),两组间比较无显著差异(P >0.05)。二项分类 logistic回归分析显示血25(OH)D3浓度与 ABI 变化无明显相关性。结论:在2型糖尿病患者中,未发现维生素 D 缺乏与下肢动脉疾病有显著相关性。
目的:探討2型糖尿病患者維生素 D 缺乏與下肢動脈疾病的相關性。方法:選取2型糖尿病患者206例,根據血25(OH)D3濃度分為維生素 D 缺乏組(<10ng/ml)和維生素 D 非缺乏組(≥10ng/ml)。採集臨床資料數據,測定下肢動脈疾病指標踝肱比(ABI)。對血25(OH)D3水平及ABI 的關繫進行方差分析及二項分類 logistic 迴歸分析。結果:在全部(206例)2型糖尿病患者中,維生素 D 缺乏組為84例(40.8%),維生素 D 非缺乏組122例(59.2%)。在維生素 D 缺乏組與非缺乏組中,已知的下肢動脈疾病危險因素(如年齡、BMI、腰圍、高血壓、吸煙、總膽固醇)無顯著差異。維生素 D 缺乏組 ABI≤0.9的24例(28.6%),維生素 D 非缺乏組 ABI≤0.9的32例(26.2%),兩組間比較無顯著差異(P >0.05)。二項分類 logistic迴歸分析顯示血25(OH)D3濃度與 ABI 變化無明顯相關性。結論:在2型糖尿病患者中,未髮現維生素 D 缺乏與下肢動脈疾病有顯著相關性。
목적:탐토2형당뇨병환자유생소 D 결핍여하지동맥질병적상관성。방법:선취2형당뇨병환자206례,근거혈25(OH)D3농도분위유생소 D 결핍조(<10ng/ml)화유생소 D 비결핍조(≥10ng/ml)。채집림상자료수거,측정하지동맥질병지표과굉비(ABI)。대혈25(OH)D3수평급ABI 적관계진행방차분석급이항분류 logistic 회귀분석。결과:재전부(206례)2형당뇨병환자중,유생소 D 결핍조위84례(40.8%),유생소 D 비결핍조122례(59.2%)。재유생소 D 결핍조여비결핍조중,이지적하지동맥질병위험인소(여년령、BMI、요위、고혈압、흡연、총담고순)무현저차이。유생소 D 결핍조 ABI≤0.9적24례(28.6%),유생소 D 비결핍조 ABI≤0.9적32례(26.2%),량조간비교무현저차이(P >0.05)。이항분류 logistic회귀분석현시혈25(OH)D3농도여 ABI 변화무명현상관성。결론:재2형당뇨병환자중,미발현유생소 D 결핍여하지동맥질병유현저상관성。
Objective:To evaluate the association between serum 25 -hydroxyvitamin D3 [25(OH)D3]and lower extremity arterial disease in patients with type 2 diabetes.Methods:206 patients with type 2 diabetes were included,which were divided into two groups based on serum 25(OH)D3 levels:vitamin D deficiency group [25(OH)D3 <10ng/ml]and vitamin D non -deficiency group [25(OH)D3≥10ng/ml].Ankle -Brachial Index (ABI),which reflected lower extremity arterial disease,was determined.Correlation between serum 25(OH)D3 levels and ABI was assessed by the Chi -square test and binary logistic regression.Results:The prevalence of vitamin D deficiency was 40.8% (84),and the non -deficiency was 59.2%(122)in all of the 206 patients with type 2 diabetes.There was no significant difference between the vitamin D deficiency group and non -deficiency group in the well -known lower extremity arterial dis-ease risk factors,such as age,BMI,waistline,hypertension,smoking and total cholesterol.The percent of ABI≤0.9 in the vitamin D deficiency group was 26. 2% (24),and the non -deficiency group was 26.2%(32),there was no significant difference either P >0.05).The binary logistic regression results showed that serum 25(OH)D3 had no obvious correlation with the variation of ABI.Conclusion:No obvious correlation was found between the vitamin D deficiency and lower extremity arterial disease in the patients with type 2 diabetes.