世界最新医学信息文摘(连续型电子期刊)
世界最新醫學信息文摘(連續型電子期刊)
세계최신의학신식문적(련속형전자기간)
World Latest Medicine Information
2015年
43期
9-10,12
,共3页
姚冬云%霍河水%赵文敏%秦晨曼%魏秋瑾%孙凯
姚鼕雲%霍河水%趙文敏%秦晨曼%魏鞦瑾%孫凱
요동운%곽하수%조문민%진신만%위추근%손개
布鲁菌病%降钙素原%c-反应蛋白%血流感染%中性粒细胞
佈魯菌病%降鈣素原%c-反應蛋白%血流感染%中性粒細胞
포로균병%강개소원%c-반응단백%혈류감염%중성립세포
Brucellosis%Procalcitonin%Bloodstream infection%sepsis%c-reactive protein%neutrofil
目的:观察血降钙素原(procalcitonin ,Pct)在本地散发伴多关节炎的布鲁菌血流感染患者中的水平及检测意义。方法回顾性分析了21例发热伴多关节炎的布鲁菌血流感染患者的Pct水平(Pct和血培养同时留取标本,用双抗体夹心电化学发光法检测)。结果布鲁菌血流感染患者Pct(0.18±0.04ng/ml)及crP值(20.91±5.43mg/l)高于正常对照组Pct值(0.03±0.01 ng/ml, P=0.039)和crP水平(2.39±0.75 mg/l,P=0.000);但明显低于大肠埃希菌血流感染患者的Pct(21.85±18.79 ng/ml,P=0.000)和crP(80.52±12.48 mg/l,P=0.000)水平;布鲁菌组的alt(188.28±84.31 U/l)和ast(122.31±77.16 U/l)水平明显高于sle大肠埃希菌血流感染组的alt(38.71±3.54 U/l,P=0.000)和ast(35.57±6.57 U/l,P=0.000),也高于正常对照组alt(26.38±7.34, P=0.000)和ast(16.48±3.08,P=0.000);布鲁菌组的中性粒细胞(neut)绝对值减少(<2.0×109/l)的比例(14/21,66.7%)显著高于大肠埃希菌血流感染组(1/21,4.8%)和对照组(2/21,9.5%),P=0.000;差异均有显著性意义。结论伴关节受累的布鲁菌血流感染患者的Pct和crP水平高于正常对照组,但明显低于大肠埃希菌组。
目的:觀察血降鈣素原(procalcitonin ,Pct)在本地散髮伴多關節炎的佈魯菌血流感染患者中的水平及檢測意義。方法迴顧性分析瞭21例髮熱伴多關節炎的佈魯菌血流感染患者的Pct水平(Pct和血培養同時留取標本,用雙抗體夾心電化學髮光法檢測)。結果佈魯菌血流感染患者Pct(0.18±0.04ng/ml)及crP值(20.91±5.43mg/l)高于正常對照組Pct值(0.03±0.01 ng/ml, P=0.039)和crP水平(2.39±0.75 mg/l,P=0.000);但明顯低于大腸埃希菌血流感染患者的Pct(21.85±18.79 ng/ml,P=0.000)和crP(80.52±12.48 mg/l,P=0.000)水平;佈魯菌組的alt(188.28±84.31 U/l)和ast(122.31±77.16 U/l)水平明顯高于sle大腸埃希菌血流感染組的alt(38.71±3.54 U/l,P=0.000)和ast(35.57±6.57 U/l,P=0.000),也高于正常對照組alt(26.38±7.34, P=0.000)和ast(16.48±3.08,P=0.000);佈魯菌組的中性粒細胞(neut)絕對值減少(<2.0×109/l)的比例(14/21,66.7%)顯著高于大腸埃希菌血流感染組(1/21,4.8%)和對照組(2/21,9.5%),P=0.000;差異均有顯著性意義。結論伴關節受纍的佈魯菌血流感染患者的Pct和crP水平高于正常對照組,但明顯低于大腸埃希菌組。
목적:관찰혈강개소원(procalcitonin ,Pct)재본지산발반다관절염적포로균혈류감염환자중적수평급검측의의。방법회고성분석료21례발열반다관절염적포로균혈류감염환자적Pct수평(Pct화혈배양동시류취표본,용쌍항체협심전화학발광법검측)。결과포로균혈류감염환자Pct(0.18±0.04ng/ml)급crP치(20.91±5.43mg/l)고우정상대조조Pct치(0.03±0.01 ng/ml, P=0.039)화crP수평(2.39±0.75 mg/l,P=0.000);단명현저우대장애희균혈류감염환자적Pct(21.85±18.79 ng/ml,P=0.000)화crP(80.52±12.48 mg/l,P=0.000)수평;포로균조적alt(188.28±84.31 U/l)화ast(122.31±77.16 U/l)수평명현고우sle대장애희균혈류감염조적alt(38.71±3.54 U/l,P=0.000)화ast(35.57±6.57 U/l,P=0.000),야고우정상대조조alt(26.38±7.34, P=0.000)화ast(16.48±3.08,P=0.000);포로균조적중성립세포(neut)절대치감소(<2.0×109/l)적비례(14/21,66.7%)현저고우대장애희균혈류감염조(1/21,4.8%)화대조조(2/21,9.5%),P=0.000;차이균유현저성의의。결론반관절수루적포로균혈류감염환자적Pct화crP수평고우정상대조조,단명현저우대장애희균조。
Objective:to survey serum procalcitonin (Pct) levels in sporadic patients with bloodstream infection of brucellosis. Method:Pct of 21 case of brucellosis being determined in parallel with hemoculture over the same period (brucellosis group), were compared with patients the corresponding period with bloodstream infection of escherichia coli(group of eco) and in normal person(control group).Result:Pct(0.18±0.04ng/ml) and crP (20.91±5.43mg/l)in patients with bloodstream infection of brucella were significantly lower than that of group of eco[Pct(21.85±18.79 ng/ml, P=0.000);crP(80.52±12.48 mg/l,P=0.000), While there was significant difference between brucellosis group and control group [Pct(0.03±0.01 ng/ml,P=0.039);crP(2.39±0.75 mg/l,P=0.000). Conclusions:different with escherichia coli infection,Pct and crP levels in patients with bloodstream infection of brucella were slightly higher than normal.