CAJ | 학술논문

[目的]分析国际和平妇幼保健院新生儿卡介苗（ BCG）疑似预防接种异常反应（ AEFI）的发病流行特征，评价本院新生儿BCG预防接种安全性。[方法]通过疑似预防接种异常反应信息管理系统，收集2010—2013年报告的接种BCG后AEFI个案数据，对相关指标进行描述性流行病学分析。[结果]2010—2013年本院新生儿BCG接种率为94．54％～95．36％，新生儿 BCG 合计接种率为95．19％。4年间，共监测到21例，报告发生率为430．86／100万剂。 BCG AEFI中，以BCG淋巴结炎为主，占95．24％，报告发生率为410．34／100万剂。[结论]本院新生儿BCG接种率维持在较高水平，新生儿接种BCG后发生AEFI以BCG淋巴结炎为主，报告发生率相对较高，在WHO估算发生率范围之内，BCG安全性尚可。
[목적]분석국제화평부유보건원신생인잡개묘（ BCG）의사예방접충이상반응（ AEFI）적발병류행특정，평개본원신생인BCG예방접충안전성。[방법]통과의사예방접충이상반응신식관리계통，수집2010—2013년보고적접충BCG후AEFI개안수거，대상관지표진행묘술성류행병학분석。[결과]2010—2013년본원신생인BCG접충솔위94．54％～95．36％，신생인 BCG 합계접충솔위95．19％。4년간，공감측도21례，보고발생솔위430．86／100만제。 BCG AEFI중，이BCG림파결염위주，점95．24％，보고발생솔위410．34／100만제。[결론]본원신생인BCG접충솔유지재교고수평，신생인접충BCG후발생AEFI이BCG림파결염위주，보고발생솔상대교고，재WHO고산발생솔범위지내，BCG안전성상가。
Objective ] To analyze the occurrence of adverse events following immunization (AEFI)of Bacille Calmette-Guerin vaccine(BCG)among neonates in IPMCH, and to evaluate the safety of BCG. [Methods] Data on BCG AEFI in 2010-2013 were collected through national AEFI information system.The descriptive methodology was used in this study . [ Results] During 2010 -2013, the coverage rate of the BCG vaccine among neonates in IPMCH was 95 .19%.And 21 BCG AEFI cases vaccinated were reported, with a reporting rate of 430.86 per 1 million doses, most of which were BCG lymphadenitis(20 cases with the incidence of 410.34 per 1 million doses). [Conclusion] The coverage rate of the BCG vaccination among neonates in IPMCH remained at high level .BCG vaccine proved safe . Most of rare vaccine reactions were BCG lymphadenitis , and the reporting rate of BCG lymphadenitis were lower than expected .