CAJ | 학술논문

目的：探讨阿维 A 联合消银颗粒治疗银屑病临床效果，以期提高治疗水平。方法：选取2011年2月～2014年2月92例银屑病患者为研究对象，分成2组，对照组46例，予常规西医治疗，治疗组46例，阿维 A 联合消银颗粒治疗，观察治疗后相关指标变化情况。结果：疗效上，对照组治愈率21．74％、总有效率82．61％，治疗组治愈率36．96％、总有效率93．48％，两组比较差异有统计学意义（P ＜0．05）；两组治疗前在 PASI 评分和 CD3＋、CD4＋、CD8＋、CD4＋／CD8＋比较差异无统计学意义（P＞0．05），治疗后和治疗前组内比较差异有统计学意义（P＜0．05），而治疗后两组 PASI 评分、CD3＋、CD4＋、CD8＋、CD4＋／CD8＋比较差异有统计学意义（P＜0．05）。结论：阿维 A 联合消银颗粒能改善银屑病临床症状，控制疾病进展。
목적：탐토아유 A 연합소은과립치료은설병림상효과，이기제고치료수평。방법：선취2011년2월～2014년2월92례은설병환자위연구대상，분성2조，대조조46례，여상규서의치료，치료조46례，아유 A 연합소은과립치료，관찰치료후상관지표변화정황。결과：료효상，대조조치유솔21．74％、총유효솔82．61％，치료조치유솔36．96％、총유효솔93．48％，량조비교차이유통계학의의（P ＜0．05）；량조치료전재 PASI 평분화 CD3＋、CD4＋、CD8＋、CD4＋／CD8＋비교차이무통계학의의（P＞0．05），치료후화치료전조내비교차이유통계학의의（P＜0．05），이치료후량조 PASI 평분、CD3＋、CD4＋、CD8＋、CD4＋／CD8＋비교차이유통계학의의（P＜0．05）。결론：아유 A 연합소은과립능개선은설병림상증상，공제질병진전。
Objective :To investigate the clinical efficacy of acitretin combined with Xiaoying granules in treat ‐ment of psoriasis ,in order to improve the treatment level .Methods :92 cases with psoriasis from Feb .2011 to Feb .2014 were chosen ,who were divided into two groups ,each group had 46 cases ,the control group were given conventional western medicine therapy ,the observation group were given acitretin combined with Xiaoying granules ,the relevant indi‐cators after treatment were observed .Results :After treatment ,the cure rate of the control group was 21 .74% ,the total efficacy was 82 .61% ,while in the observation group was 36 .96% and 93 .48% ,which had significant difference(P< 0 . 05) ,the PASI score and CD3 + 、CD4 + 、CD8 + 、CD4 + /CD8 + of two groups before treatment had no significant difference(P> 0 .05) .Compared with before treatment ,which had obviously differences(P< 0 .05) .The PASI score ,CD3 + 、CD4 + 、CD8 + 、CD4 + /CD8 + of two groups after treatment had obviously difference (P < 0 .05) .Conclusion :Acitretin combined with silver particles can improve the psoriasis symptoms and control the disease progression .