CAJ | 학술논문

目的：探讨薄层液基细胞学检测（Thinprep cytoligic test， TCT）在诊断非典型鳞状细胞的意义。方法回顾性分析某医院2012年7月至2014年7月期间 TCT 标本中诊断为非典型鳞状细胞患者的结局。结果349例宫颈非典型鳞状细胞中，152例患者 HPV 阳性，44．7％存在宫颈上皮内瘤变或宫颈癌；197例 HPV 阴性患者中，8例患者存在宫颈上皮内瘤变或宫颈癌。同时非典型鳞状细胞的诊断与年龄存在相关性，年龄在40岁以上的妇女被诊断为 ASC 的人数较多。结论宫颈 TCT 及 HPV 筛查对于宫颈癌前病变及宫颈癌的早期发现有重要价值。应提高对 ASC 认识及对患者重视，以免耽误宫颈病变的诊断和治疗。
목적：탐토박층액기세포학검측（Thinprep cytoligic test， TCT）재진단비전형린상세포적의의。방법회고성분석모의원2012년7월지2014년7월기간 TCT 표본중진단위비전형린상세포환자적결국。결과349례궁경비전형린상세포중，152례환자 HPV 양성，44．7％존재궁경상피내류변혹궁경암；197례 HPV 음성환자중，8례환자존재궁경상피내류변혹궁경암。동시비전형린상세포적진단여년령존재상관성，년령재40세이상적부녀피진단위 ASC 적인수교다。결론궁경 TCT 급 HPV 사사대우궁경암전병변급궁경암적조기발현유중요개치。응제고대 ASC 인식급대환자중시，이면탐오궁경병변적진단화치료。
Objective To investigate the significance of thinprep cytoligic test (TCT) in the diagnosis of atypical squamous cells.Methods A retrospective analysis was conducted among TCT samples from which those with atypical squamous cells were diag-nosed from July 2012 till July 2014.Results Of all 349 cases, 152 were HPV-positive, and 44.7% were diagnosed with cervical intraepithelial neoplasia or cervical cancer; among 197 cases of HPV-negative patients, 8 cases of patients were with cervical intraepi-thelial neoplasia or cervical cancer.since atypical squamous cells were correlated with age, women older than 40 years old composed the main part of ASC.Conclusion TCT was meaningful for an early detection of cervical lesions and cervical cancer.Increasing awareness of ASC and attention to patients may avoid delay in diagnosis and treatment of cervical lesions.