CAJ | 학술논문

目的：分析甲状腺结节细针穿刺细胞学检查( fine-needle aspiration biopsy,FNAB)的应用价值。方法回顾性分析578例行FNAB检查患者的临床病理资料。应用Bethesda报告系统诊断分类,对其中手术治疗的132例患者的组织病理与细胞病理进行对照。结果132例患者的FNAB检查结果应用Bethesda报告系统诊断分类,将标本分为6类,分别是：标本无法诊断占7.6%；良性病变占43.2%；意义不明确的细胞非典型病变占19.7%；滤泡性肿瘤及可疑滤泡性肿瘤占5.3%；可疑恶性肿瘤占6.8%；恶性肿瘤占17.4%。将FNAB检查结果与组织病理对照后发现：甲状腺结节细针穿刺判断甲状腺良恶性结节的灵敏度及特异度分别为81.1%和97.6%,阳性预测值为93.8%。结论甲状腺细针穿刺对于鉴别甲状腺良恶性结节是可靠的方法。
목적：분석갑상선결절세침천자세포학검사( fine-needle aspiration biopsy,FNAB)적응용개치。방법회고성분석578례행FNAB검사환자적림상병리자료。응용Bethesda보고계통진단분류,대기중수술치료적132례환자적조직병리여세포병리진행대조。결과132례환자적FNAB검사결과응용Bethesda보고계통진단분류,장표본분위6류,분별시：표본무법진단점7.6%；량성병변점43.2%；의의불명학적세포비전형병변점19.7%；려포성종류급가의려포성종류점5.3%；가의악성종류점6.8%；악성종류점17.4%。장FNAB검사결과여조직병리대조후발현：갑상선결절세침천자판단갑상선량악성결절적령민도급특이도분별위81.1%화97.6%,양성예측치위93.8%。결론갑상선세침천자대우감별갑상선량악성결절시가고적방법。
Objective To study the clinical value of fine-needle aspiration cytology of thyroid nodule. Methods A retrospective review was performed among 578 consecutive cases of FNA cytology of thyroid nod-ules. Cytologic diagnoses were classified as non-diagnostic or unsatisfactory, benign, atypia of unknown signifi-cance/follicular lesion of unknown significance( AUS/FLUS) , suspicious for follicular neoplasm( SFN) , suspi-cious for malignancy and malignancy based on the Bethesda system. The discrepancies between initial cytologic diagnoses and histologic diagnoses were evaluated among 132 surgical specimens. Results Among 132 cases who underwent surgery, FNAs were 7. 6% unsatisfactory, 43. 2% benign,19. 7% AUS/FLUS, 5. 3% SFN, 6. 8% suspicious, and 17. 4% malignant. The sensitivity, specificity and positive predictive value of thyroid FNA for the diagnosis of malignancy were 81. 1%,97. 6%and 93. 8%respectively. Conclusions Fine-needle aspiration is a reliable method for identifying benign and malignant thyroid nodules.