CAJ | 학술논문

目的：评价超声引导真空辅助活检( ultrasound-guided vacuum-assisted biopsy, UGVAB)系统对具有适应证的乳腺多发病灶和单发病灶诊断性切除的疗效。方法选择2012年3月至2014年2月期间的345例乳腺小病灶患者,在超声引导下通过UGVAB系统连接旋切刀穿刺到超声定位病变,尽可能完全切除病变。术后对诊断为良性病变的患者进行随访和超声检查。结果大多数患者在手术过程中有较好的顺应性。多灶性病变组不适症状发生率(18/157)高于单发病灶组(3/188),差异有统计学意义(P=0.000)；所有病灶均获得准确的病理诊断,多灶性病变组中癌或ADH的发生率(14/157)高于单发病灶组(3/188),差异有统计学意义(P=0.004)；多灶性病变组患者的术后并发症发生率及良性病变残留率均高于单发病变患者,差异均有统计学意义(P<0.05),发生术后并发症的良性肿瘤患者均不需进一步手术治疗。良性病变患者在术后6个月的复查中无假阴性。结论超声引导真空辅助活检系统对具有适应证的乳腺多灶性病变进行诊断性切除具有良好效果,值得在临床上推广应用。
목적：평개초성인도진공보조활검( ultrasound-guided vacuum-assisted biopsy, UGVAB)계통대구유괄응증적유선다발병조화단발병조진단성절제적료효。방법선택2012년3월지2014년2월기간적345례유선소병조환자,재초성인도하통과UGVAB계통련접선절도천자도초성정위병변,진가능완전절제병변。술후대진단위량성병변적환자진행수방화초성검사。결과대다수환자재수술과정중유교호적순응성。다조성병변조불괄증상발생솔(18/157)고우단발병조조(3/188),차이유통계학의의(P=0.000)；소유병조균획득준학적병리진단,다조성병변조중암혹ADH적발생솔(14/157)고우단발병조조(3/188),차이유통계학의의(P=0.004)；다조성병변조환자적술후병발증발생솔급량성병변잔류솔균고우단발병변환자,차이균유통계학의의(P<0.05),발생술후병발증적량성종류환자균불수진일보수술치료。량성병변환자재술후6개월적복사중무가음성。결론초성인도진공보조활검계통대구유괄응증적유선다조성병변진행진단성절제구유량호효과,치득재림상상추엄응용。
Objective To compare and assess the value of ultrasound-guided vacuum-assisted biopsy sys-tem ( UGVAB) in the diagnosis and excision of breast multifocal lesions and isolated lesions. Methods 345 patients were retrospectively analyzed and received ultrasound-guided diagnostic breast biopsy procedures per-formed by the 8-gauge vacuum-assisted biopsy approach from March 2012 to February 2014. All lesions were ex-cised as completely as possible. One year and a half after operation, patients diagnosed as pathological benign lesions were followed up through physical and ultrasound examination. Results All lesions were obtained accu-rate pathological diagnosis. After 6 months of postoperative follow-up,all benign lesions did not appear apparent false-negative results. The rates of malignant or premalignant findings and postoperative complications were signifi-cantly higher in patients with multifocal lesions than in patients with single lesion (P<0. 05). Postoperative com-plications in patients with benign tumors received no further surgery. Conclusions Ultrasound-guided vacuum-as-sisted biopsy system should be a routinely method of choice in diagnosing and treating breast multifocal lesions.