国际病毒学杂志
國際病毒學雜誌
국제병독학잡지
INTERNATIONAL JOURNAL OF VIROLOGY
2015年
4期
228-231
,共4页
林毅枢%张钢%唐科伟%李保国
林毅樞%張鋼%唐科偉%李保國
림의추%장강%당과위%리보국
良性前列腺增生%细菌性前列腺炎%人乳头瘤病毒%前列舒乐颗粒%治疗方案
良性前列腺增生%細菌性前列腺炎%人乳頭瘤病毒%前列舒樂顆粒%治療方案
량성전렬선증생%세균성전렬선염%인유두류병독%전렬서악과립%치료방안
Benign prostatic hyperplasia%Bacterial prostatitis%Human papilloma virus%Qianlieshule granule%Therapeutic scheme
目的 分析良性前列腺增生(BPH)合并细菌性前列腺炎与人类乳头瘤病毒的关系以及应用不同治疗方案的临床疗效,总结最佳的临床治疗方案.方法 将120例BPH合并细菌性前列腺炎患者随机分为常规组及观察组两组,每组60例.常规组接受常规西医治疗,观察组在常规组治疗的同时给予前列舒乐颗粒口服治疗.再选用未婚无性经历男性患者39例作为对照组,对所有研究对象前列腺液取材后行HPV(人乳头瘤病毒总型)PCR检测,分别对比常规组与观察组治疗前后的国际前列腺症状(I-PSS)评分、慢性前列腺炎症状(NIH-CPSI)评分及前列腺体积改善情况.同时对比两组临床治疗总有效率及药物副作用发生率.结果 对照组研究对象HPV(总型)呈阴性,良性前列腺增生(BPH)合并细菌性前列腺炎患者阳性率为17.5% (21/120),两组患者存在差异(P<0.05),治疗前两组I-PSS评分、NIH-CPSI评分及前列腺体积比较均未见统计学差异(P>0.05),但治疗1个月后,观察组以上指标改善均明显优于常规组(P<0.05).同时观察组治疗总有效率明显优于常规组(P<0.05).结论 良性前列腺增生(BPH)合并细菌性前列腺炎与人乳头瘤病毒关系密切,并且在常规治疗的基础上应用前列舒乐颗粒治疗可有效的提高临床治疗效果.
目的 分析良性前列腺增生(BPH)閤併細菌性前列腺炎與人類乳頭瘤病毒的關繫以及應用不同治療方案的臨床療效,總結最佳的臨床治療方案.方法 將120例BPH閤併細菌性前列腺炎患者隨機分為常規組及觀察組兩組,每組60例.常規組接受常規西醫治療,觀察組在常規組治療的同時給予前列舒樂顆粒口服治療.再選用未婚無性經歷男性患者39例作為對照組,對所有研究對象前列腺液取材後行HPV(人乳頭瘤病毒總型)PCR檢測,分彆對比常規組與觀察組治療前後的國際前列腺癥狀(I-PSS)評分、慢性前列腺炎癥狀(NIH-CPSI)評分及前列腺體積改善情況.同時對比兩組臨床治療總有效率及藥物副作用髮生率.結果 對照組研究對象HPV(總型)呈陰性,良性前列腺增生(BPH)閤併細菌性前列腺炎患者暘性率為17.5% (21/120),兩組患者存在差異(P<0.05),治療前兩組I-PSS評分、NIH-CPSI評分及前列腺體積比較均未見統計學差異(P>0.05),但治療1箇月後,觀察組以上指標改善均明顯優于常規組(P<0.05).同時觀察組治療總有效率明顯優于常規組(P<0.05).結論 良性前列腺增生(BPH)閤併細菌性前列腺炎與人乳頭瘤病毒關繫密切,併且在常規治療的基礎上應用前列舒樂顆粒治療可有效的提高臨床治療效果.
목적 분석량성전렬선증생(BPH)합병세균성전렬선염여인류유두류병독적관계이급응용불동치료방안적림상료효,총결최가적림상치료방안.방법 장120례BPH합병세균성전렬선염환자수궤분위상규조급관찰조량조,매조60례.상규조접수상규서의치료,관찰조재상규조치료적동시급여전렬서악과립구복치료.재선용미혼무성경력남성환자39례작위대조조,대소유연구대상전렬선액취재후행HPV(인유두류병독총형)PCR검측,분별대비상규조여관찰조치료전후적국제전렬선증상(I-PSS)평분、만성전렬선염증상(NIH-CPSI)평분급전렬선체적개선정황.동시대비량조림상치료총유효솔급약물부작용발생솔.결과 대조조연구대상HPV(총형)정음성,량성전렬선증생(BPH)합병세균성전렬선염환자양성솔위17.5% (21/120),량조환자존재차이(P<0.05),치료전량조I-PSS평분、NIH-CPSI평분급전렬선체적비교균미견통계학차이(P>0.05),단치료1개월후,관찰조이상지표개선균명현우우상규조(P<0.05).동시관찰조치료총유효솔명현우우상규조(P<0.05).결론 량성전렬선증생(BPH)합병세균성전렬선염여인유두류병독관계밀절,병차재상규치료적기출상응용전렬서악과립치료가유효적제고림상치료효과.
Objective To analysis the relationship between Human papilloma virus and benign prostatic hyperplasia (BPH) with bacterial prostatitis and to investigate clinical efficiencies of different treatment methods,so as to provide a best therapeutic scheme to the doctor.Methods One hundred and twenty cases of BPH complicated with bacterial prostatitis were randomly divided into the routine group and the observation group,60 cases in each group.The routine group was received conventional western medicine treatment and the observation group was received Qianlieshule granule and western medicine treatment.Another thirtynine unmarried male patients with no sexual experience were selected as control group.HPV (human papilloma virus type) PCR detection was used to analyze prostate fluid samples of all subjects before and after treatment respectively.International Prostate Symptom Score (I-PSS),chronic prostatitis symptom score (NIH-CPSI) and prostatic volume improvement were compared between the routine group and the observation group before and after treatment.The total efficiency and the side effects of drugs were compared between the two groups.Results There was no positive case of HPV in control groups.The positive rate of HPV in the routine group and the observation group was 17.5% (21/120).The difference was statistically significant (P< 0.05).There was no significant difference of International Prostate Symptom Score (I-PSS),chronic prostatitis symptom score (NIH-CPSI) between two groups before treatment (P > 0.05).The difference was significant with one month treatment (P < 0.05).The total efficiency of the observation group was higher than that of the routine group (P < 0.05).Conclusions BPH complicated with bacterial prostatitis was closely related with human papilloma virus infection,and therapeutic scheme of Qianlieshule granule combined with conventional treatment can improve the effect of clinical treatment effectively.