陕西中医
陝西中醫
협서중의
SHAANXI JOURNAL OF TRADITIONAL CHINESE MEDICINE
2015年
8期
971-973
,共3页
心脏病/中西医结合疗法%硫酸氢氯吡格雷片%芪参益气滴丸
心髒病/中西醫結閤療法%硫痠氫氯吡格雷片%芪參益氣滴汍
심장병/중서의결합요법%류산경록필격뢰편%기삼익기적환
Heart diseases /integrated Chinese traditional and western medicine therapy%Plavix%Qishen Yiqi dripping pills
目的：探讨芪参益气滴丸结合波利维治疗对冠心病炎症因子 C 反应蛋白（CRP）、纤维蛋白质（FIB）的影响。方法：选择在我院诊治的冠心病患者80例，根据随机抽签原则分为对照组与治疗组各40例，两组都给予常规治疗，在此基础上对照组口服波利维治疗，治疗组口服芪参益气滴丸结合波利维治疗，均治疗4周。结果：所有患者都完成治疗，治疗组与对照组的有效率分别为95．0％和87．5％，治疗组的治疗有效率明显高于对照组（P＜0．05）。两组治疗后的血浆 CRP 与 FIB 表达值都明显下降（P＜0．05），同时治疗后治疗组的血浆 CRP 与 FIB值明显低于对照组（P＜0．05）。所有患者治疗后随访6个月，治疗组的再次心肌梗死、心力衰竭、心绞痛反复发作、冠脉血运重建等不良反应发生情况明显少于对照组（P＜0．05）。结论：芪参益气滴丸结合波利维治疗冠心病能有效降低 CRP 与 FIB 的表达，提高总体治疗效果，降低远期心血管事件的发生，有很好的应用价值。
目的：探討芪參益氣滴汍結閤波利維治療對冠心病炎癥因子 C 反應蛋白（CRP）、纖維蛋白質（FIB）的影響。方法：選擇在我院診治的冠心病患者80例，根據隨機抽籤原則分為對照組與治療組各40例，兩組都給予常規治療，在此基礎上對照組口服波利維治療，治療組口服芪參益氣滴汍結閤波利維治療，均治療4週。結果：所有患者都完成治療，治療組與對照組的有效率分彆為95．0％和87．5％，治療組的治療有效率明顯高于對照組（P＜0．05）。兩組治療後的血漿 CRP 與 FIB 錶達值都明顯下降（P＜0．05），同時治療後治療組的血漿 CRP 與 FIB值明顯低于對照組（P＜0．05）。所有患者治療後隨訪6箇月，治療組的再次心肌梗死、心力衰竭、心絞痛反複髮作、冠脈血運重建等不良反應髮生情況明顯少于對照組（P＜0．05）。結論：芪參益氣滴汍結閤波利維治療冠心病能有效降低 CRP 與 FIB 的錶達，提高總體治療效果，降低遠期心血管事件的髮生，有很好的應用價值。
목적：탐토기삼익기적환결합파리유치료대관심병염증인자 C 반응단백（CRP）、섬유단백질（FIB）적영향。방법：선택재아원진치적관심병환자80례，근거수궤추첨원칙분위대조조여치료조각40례，량조도급여상규치료，재차기출상대조조구복파리유치료，치료조구복기삼익기적환결합파리유치료，균치료4주。결과：소유환자도완성치료，치료조여대조조적유효솔분별위95．0％화87．5％，치료조적치료유효솔명현고우대조조（P＜0．05）。량조치료후적혈장 CRP 여 FIB 표체치도명현하강（P＜0．05），동시치료후치료조적혈장 CRP 여 FIB치명현저우대조조（P＜0．05）。소유환자치료후수방6개월，치료조적재차심기경사、심력쇠갈、심교통반복발작、관맥혈운중건등불량반응발생정황명현소우대조조（P＜0．05）。결론：기삼익기적환결합파리유치료관심병능유효강저 CRP 여 FIB 적표체，제고총체치료효과，강저원기심혈관사건적발생，유흔호적응용개치。
Objective : To discuss the inflammatory cytokines C‐reactive protein (CRP ) ,fibrinogen (FIB ) effects of Qishen Yiqi dripping pills combined plavix for treating coronary heart disease .Methods :From february 2012 to january 2015 ,selected 80 patients with coronary heart disease accorded to the principle of random draw were equally di ‐vided into control and treatment group with 40 patients ,two groups were given conventional treatment cardiology ,on this basis ,the control group was treated with plavix treatment ,the treatment group was treated with Qishen Yiqi dripping pills combined plavix ,all treatment for 4 weeks .Results :All patients were completed the treatment ,the response rates in the treatment group and the control group were 95 .0% and 87 .5% ,respectively that the treatment group was signifi‐cantly higher (P < 0 .05) .The plasma CRP and FIB expression values after treatment were significantly decreased (P <0 .05) ,while the value of plasma CRP and FIB in the treatment group after treatment were significantly lower than those in the control group (P < 0 .05) .All patients were followed up for six months ,the again myocardial infarction ,heart failure ,recurrent angina ,coronary revascularization ,and other adverse effects in the treatment group were significantly less than those in the control group (P < 0 .05) .Conclusion :The Qishen Yiqi dripping pills combined plavix for trea‐ting coronary heart disease can reduce the expression of CRP and FIB ,improve the overall treatment effect ,reduce the in‐cidence of long‐term cardiovascular events that has very good values .
