实用医院临床杂志
實用醫院臨床雜誌
실용의원림상잡지
PRACTICAL JOURNAL OF CLINICAL MEDICINE
2015年
5期
10-12,13
,共4页
狼疮性肾炎%目标治疗
狼瘡性腎炎%目標治療
랑창성신염%목표치료
Lupus nephritis%Target therapy
狼疮性肾炎是系统性红斑狼疮的常见并发症,易反复发作,致死致残率高,在本文中我们结合当前研究进展对该病的目标治疗策略进行了探讨。对于狼疮性肾炎患者,应尽早起始治疗,通过选用敏感免疫抑制药物,并结合运用新的治疗手段,以达到疾病完全缓解为首要目标。在此基础上维持疾病长期缓解,同时提高治疗的依从性,逐步减少激素用量,防治药物不良反应,从而改善患者的预后。
狼瘡性腎炎是繫統性紅斑狼瘡的常見併髮癥,易反複髮作,緻死緻殘率高,在本文中我們結閤噹前研究進展對該病的目標治療策略進行瞭探討。對于狼瘡性腎炎患者,應儘早起始治療,通過選用敏感免疫抑製藥物,併結閤運用新的治療手段,以達到疾病完全緩解為首要目標。在此基礎上維持疾病長期緩解,同時提高治療的依從性,逐步減少激素用量,防治藥物不良反應,從而改善患者的預後。
랑창성신염시계통성홍반랑창적상견병발증,역반복발작,치사치잔솔고,재본문중아문결합당전연구진전대해병적목표치료책략진행료탐토。대우랑창성신염환자,응진조기시치료,통과선용민감면역억제약물,병결합운용신적치료수단,이체도질병완전완해위수요목표。재차기출상유지질병장기완해,동시제고치료적의종성,축보감소격소용량,방치약물불량반응,종이개선환자적예후。
Lupus nephritis is a common complication of systemic lupus erythematosus (SLE)that is easy to relapse and often related to high morbidity and mortality.In this paper,target therapeutic strategies for these patients are discussed .In summary,the treat-ments for patients with lupus nephritis should be initiated early in the disease process with the use of effective immunosuppressive drugs and novel treatment to achieve the primary goal of disease complete .New treatment strategies are to be considered when it is hard to control the disease.On this basis,we should sustain remission along with improvement of the treatment compliance and gradual decrease of steroid dose to reduce the adverse drug effects ,and thus improve the prognosis of the patients .